Abstract
A series of 7-{2-(2-aminothiazol-4-yl)-2-Z-(γ-lacton-3-yl) oxyiminoacetamidol} cephalosporins with various substituents at the 3-position in cephem nucleus were synthesized and evaluated microbiologically. The tested compounds showed potent activities but were somewhat less active than cefotaxime or cefixime against a wide variety of Gram-positive and Gram-negative bacteria.
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Suh, KH., Park, JW. Synthesis and antibacterial activity of new cephalosporins with lactonyloxyimino moiety. Arch. Pharm. Res. 17, 87–92 (1994). https://doi.org/10.1007/BF02974229
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DOI: https://doi.org/10.1007/BF02974229