Abstract
A methanol extract of the roots ofBupleurum longiradiatum (Umbelliferae) showed antiinflammatory activity in rats. Hexane, chloroform, butanol, and aqueous fractions from the methanol extract were tested with the result that only the hexane fraction exhibited positive activity. Fractionation of the hexane extract resulted in isolation of arborinone as an active principle.
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Literature Cited
Akihisa, T., Yamamoto, K., Tamura, T., Kimura, Y., Iida, T., Nambara, T. and Chang, F. C., Triterpenoid ketones fromLingnania chungii McClure: Arborinone, friedelin and glutinone.Chem. Pharm. Bull., 43, 789 (1992).
Nishimoto, K., Ito, M., Natori, S. and Ohmoto, T., The structures of arundoin, cylindrin and femenol. Triterpenoids of femane and arborane groups ofImperata cylindrica var.koenigii.Teterahedron, 24, 735 (1968).
Perry, L. M.,Medicinal plants of East and Southesat Asia. MIT, Cambridge, 1980, p.413.
Singh, H. and Ghosh, M. N., Modified plethysmometer for measuring foot volume of unanesthetized rats.J. Pharm. Pharmac., 20, 316 (1968).
Winter, C. A., Risley, E. A. and Nuss, G. W., Carrageenin-induced edema in hind paw of the rat as an assay for antiinflammatory drugs.J. Pharmacol. Exptl. Therap., 111, 544 (1962).
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Woo, W.S., Choi, J.S. Antiinflammatory principle ofBupleurum longiradiatum roots. Arch. Pharm. Res. 16, 29–31 (1993). https://doi.org/10.1007/BF02974124
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DOI: https://doi.org/10.1007/BF02974124