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Synthesis and anticonvulsant and anti inflammatory activities of new 3-aryl/alkylimino-1-methylindol-2-ones

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Abstract

Titled compounds have been synthesized by treating the 3-aryl/alkyliminoindol-2-ones with dimethyl-sulfate in presence of 10% sodium hydroxide and screened for their anticonvulsant and anti-inflammatory activities. The compounds having 1-naphthyl andp-chlorophenyl substituents are the most potent compounds in the series.

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Authors and Affiliations

  1. Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, 221 005, Varanasi, India

    Girija Shankar Singh, Nadeem Siddiqui & Surendra Nath Pandeya

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  1. Girija Shankar Singh
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  2. Nadeem Siddiqui
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  3. Surendra Nath Pandeya
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Singh, G.S., Siddiqui, N. & Pandeya, S.N. Synthesis and anticonvulsant and anti inflammatory activities of new 3-aryl/alkylimino-1-methylindol-2-ones. Arch. Pharm. Res. 15, 272–274 (1992). https://doi.org/10.1007/BF02974069

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  • DOI: https://doi.org/10.1007/BF02974069

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