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Anticariogenic β-carboline alkaloids fromCommelina communis

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Abstract

The methanolic extract ofCommelina communis (aerial part) showed antibacterial activity aganist a cariogenic bacterium,Streptococcus mutans OMZ 176. The active principles were identified to be β-carboline alkaloids, 1-carbomethoxy-β-carboline, norharman and harman, which were bactericidal in the minimal inhibitory concentration (MIC) of 100 μg/ml against the strain.

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Authors and Affiliations

  1. College of Pharmacy, Chungnam National University, 305-764, Taejon

    Kihwan Bae & Wonjun Seo

  2. Graduate School of Environmental Studies, Yeungnam University, 713-800, Kyungsan, Korea

    Taeho Kwon

  3. College of Pharmacy, Yeungnam University, 713-800, Kyungsan, Korea

    Soohyun Baek, Shinwoong Lee & Kapduck Jin

Authors
  1. Kihwan Bae
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  2. Wonjun Seo
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  3. Taeho Kwon
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  4. Soohyun Baek
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  5. Shinwoong Lee
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  6. Kapduck Jin
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Bae, K., Seo, W., Kwon, T. et al. Anticariogenic β-carboline alkaloids fromCommelina communis . Arch. Pharm. Res. 15, 220–223 (1992). https://doi.org/10.1007/BF02974058

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  • DOI: https://doi.org/10.1007/BF02974058

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