Skip to main content
SpringerLink
Log in

Coumarin glycosides from the roots ofAngelica dahurica

  • Original Articles
  • Published:
Archives of Pharmacal Research Aims and scope Submit manuscript

Abstract

From the roots ofAngelica dahurica Bentham et Hooker (Umbelliferae), five known coumarin glucosides together with adenosine have been isolated and identified as nodakenin, 3′-hydroxymarmesinin, tert.-O-β-D-glucopyranosyl-byakangelicin, sec.-O-β-D-glucopyranosyl-byakangelicin and scopolin. This is the first report of the occurrence of these compounds in this plant.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. Perry, L. M.: Medicinal plants of East and Southeast Asia: Attributed properties and uses. The MIT Press, Cambridge, p. 411 (1980).

    Google Scholar 

  2. Hsu, H.-Y., Chen, Y.-P., Shen, S.-J., Hsu, C.-C. and Chang, H.-C.: Oriental materia medica, a concise guide. Oriental Haling Arts Institute, p. 45 (1986).

  3. Shlyun'ko, E. K., Shagova, L. I., Tikhomirova, L. I. and Nadezhina, T. P.: Coumarins of the roots ofAngelica dahurica. Chem. Nat. Compds. 241 (1977).

  4. Kozawa, M. Baba, K., Okuda K., Fukumoto, T., and Hata, K.: Studies on the chemical compounds of “Bai Zhi”. on coumarins from “Japanese Bai Zhi”.Shoyakugaku Zasshi 35, 90 (1981).

    CAS  Google Scholar 

  5. Shin K. H., Moon, K. H. and Woo, W. S.: Two minor furanocoumarins ofAngelica dahurica.Arch. Pharm. Res. 14, 165 (1991).

    Article  Google Scholar 

  6. Kim, C. M., Heo, M. Y., Kim, H. P., Sin, K. S. and Pachaly, P.: Pharmacological activities of water extracts of Umbelliferae plants.Arch. Pharm. Res. 14 87 (1991).

    Article  PubMed  CAS  Google Scholar 

  7. Amoros, H. and Girre, R. L.: Structure of two antiviral triterpene saponins fromAnagallis arvensis.Phytochemistry 26, 787 (1987).

    Article  CAS  Google Scholar 

  8. Murray, R. D. G., Mendez, J. and Brown, S. A.: The natural coumarins. Occurrence, chemistry and biochemistry, John Wiley and Sons Ltd., New York (1982).

    Google Scholar 

  9. Matano, Y., Okuyama, T., Shibata, S., Hoson, M., Kawada, T., Osada, H. and Noguchi, T.: Studies on coumarins of a Chinese drug “Qian-Hu”, VII. Structures of new coumarin-glycosides of Zi-Hua Qian-Hu and effect of coumarin-glycosides on human platelet aggregation.Planta Med. 135 (1986).

  10. Ahluwalia, V. K., Boyd, D. R., Jain, A. K., Khanduri, C. H. and Sharma N. D.: Furanocoumarin glucosides from the seeds ofApium graveolenes.Phytochemistry 27, 1181 (1988).

    Article  CAS  Google Scholar 

  11. Steck, W. and Mazurek, M.: Identification of natural coumarins by NMR spectroscopy.Lloydia 35, 418 (1972).

    PubMed  CAS  Google Scholar 

  12. Sakakibara, I., Okuyama, T. and Shibata, S.: Studies on coumarins of a Chinese drug “Qian-Hu”. IV. Coumarins from “Zi-Hua Qian-Hu”.Planta Med. 50, 117 (1984).

    Article  PubMed  CAS  Google Scholar 

  13. Lemmich J., Havelund, S. and Thastrup, O.: Dihydrofurocoumarin glucosides fromAngelica archangelica andAngelica silvestris.Phytochemistry 22, 553 (1983).

    Article  CAS  Google Scholar 

  14. Okuyama, T., Takata, M. and Shibata, S.: Structures of linear furano- and simple coumarin glycosides of Bai-Hua Qian-Hu.Planta Med. 55, 64 (1989).

    Article  PubMed  CAS  Google Scholar 

  15. Gu Z.-M., Zhang, D.-X., Yang X.-W., Hattori, M. and Namba, T.: Isolation of two new comarin glycosides fromNotopterygium forbesii and evaluation of Chinese crude drug, Qiang-Huo, the underground parts ofN. incisum andN. forbesii, by high-performance liquid chromatography.Chem. Pharm. Bull. 38, 2498 (1990).

    PubMed  CAS  Google Scholar 

  16. Lee, K.-H. and Soine, T. O.: Coumarins IX: Coumarins ofSphenosciadium capitellatum, (A. Gray).J. Pharm. Sci. 58, 675 (1969).

    Article  PubMed  CAS  Google Scholar 

  17. Okuyama, T., Kawasaki, C., Shibata, S., Hoson, M., Kawada, T., Osada, H. and Noguchi, T.: Effect of oriental plant drugs on platelet aggregation II. Effect of Qian-Hu coumarins on human, platelet aggregation.Planta Med. 132 (1986).

  18. Asahara, T., Sakakibara, I., Okuyama, T. and Shibata, S.: Studies on coumarins of a Chinese drug “Qian-Hu”, V. Coumarin-glycosides from “Zi-Hua Qian-Hu”.Planta Med. 488 (1984).

  19. Lee, K.-H. and Soine, T. O.: Coumarins X: Spectral studies on some linear furanocoumarins.J. Pharm. Sci. 58, 681 (1969).

    Article  PubMed  CAS  Google Scholar 

  20. Murray, K. D. H. and Jorge, Z. D.: A simple method for differentiating between angular and linear 5-methoxyfuranocoumarins.Phytochemistry 23, 697 (1984).

    Article  CAS  Google Scholar 

  21. Porter, Q. N. and Baldas, J.: Mass spectrometry of heterocyclic compounds. Wiley-Interscience, New York, p. 147 (1971).

    Google Scholar 

  22. Perel'son, M. E., Sheinker, Yu, N. and Syrova, G. P.: NMR spectra of natural coumarin derivatives. II. Furocoumarins.Chem. Nat. Compds. 7, 557 (1971).

    Article  Google Scholar 

  23. Harkar, S., Razdan, T. K. and Waight, E. S.: Steroids, chromone and coumarins fromAngelica officinalis.Phytochemistry 23, 419 (1984).

    Article  CAS  Google Scholar 

  24. Rondest, J., Das, B. C., Ricroch, M.-N., Kan-Fan, C., Potier, P. and Polonsky, J.: Plantes malgaches-III. Etude des constituants deEvodia belahe Baillon.Phytochemistry 7, 1019 (1968).

    Article  CAS  Google Scholar 

  25. Thatrup, O. and Lemmich, J.: Furocoumarin glucosides ofAngelica archangelica subspecieslitoralis.Phytochemistry 22, 2035 (1983).

    Article  Google Scholar 

  26. Kuroyanagi, M., Shiotsu, M., Ebihara, T., Kawai H., Ueno, A. and Fukushima, S.: Chemical studies onViburnum awabuki K. Koch.Chem. Pharm. Bull. 34, 4012 (1986).

    CAS  Google Scholar 

  27. Son, K. H., Do, J. C. and Kang, S. S.: Isolation of adenosine from the rhizomes ofPolygonatum sibiricum.Arch. Pharm. Res. 14, 193 (1991).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. College of Pharmacy, Kangweon National University, 220-701, Chuncheon, Korea

    Seoung Han Kim & Chang Min Kim

  2. Natural Products Research Institute, Seoul National University, 110-460, Seoul, Korea

    Sam Sik Kang

Authors
  1. Seoung Han Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sam Sik Kang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Chang Min Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kim, S.H., Kang, S.S. & Kim, C.M. Coumarin glycosides from the roots ofAngelica dahurica . Arch. Pharm. Res. 15, 73–77 (1992). https://doi.org/10.1007/BF02973988

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02973988

Keywords

Search

Navigation