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Complications de l’anesthésie topique du pharynx avant endoscopie digestive supérieure

Complications of topical anesthesia of the pharynx before upper digestive endoscopy

  • Published:
Acta Endoscopica

Résumé

L’anesthésie topique du pharynx avant les endoscopies digestives supérieures est couramment pratiquée par une majorité d’endoscopistes en vue d’améliorer le confort et la qualité de l’examen.

Aucune étude, à ce jour, ne permet cependant d’affirmer l’utilité de cette pratique.

Bien plus, elle peut entraîner des effets indésirables potentiellement graves, que nous revoyons en détail, à la lumière des données pharmacologiques.

Nous comparons les anesthésiques topiques couramment employés et terminons par les recommandations afin de prévenir et de traiter les éventuelles complications.

Summary

The topical anaesthesia of the pharynx before upper digestive endoscopies is usually performed by most of the endoscopists in view to improve comfort and quality of the examination.

Until now, no study have assessed the usefulness of this practice.

Moreover it can involve potentially serious undesirable effects that we re-examine in detail, in the light of the pharmacological data.

We compare the topical anaesthetic drugs usually employed and propose recommendations in order to prevent and to treat the complications.

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Références

  1. ADRIANI J., CAMPBELL D. — Fatalities following topical application of local anesthetics to mucous membranes.JAMA, 1956,162, 1527–1530.

    Article  CAS  Google Scholar 

  2. ADRIANI J. The clinical pharmacology of local anesthetics.Clin. Pharmacol. Ther., 1960,1, 645–673.

    CAS  Google Scholar 

  3. ADRIANI J., ZEPERNICK R. — Some recent studies on the clinical pharmacology of local anesthetics of practical significance.Ann. Surg., 1963,158, 666–671.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. ADRIANI J., ZEPERNICK R. — Allergic reactions to local anesthetics.South. Med. J., 1981,74, 694–699.

    Article  CAS  PubMed  Google Scholar 

  5. ALDRETE J.A., JOHNSON D.A. — Allergy to local anesthetics.JAMA, 1969,207, 356–357.

    Article  CAS  PubMed  Google Scholar 

  6. ALDRETE J.A., JOHNSON D.A. — Evaluation of intracutaneous testing for investigation of allergy to local anesthetic agents.Anesth. Analg., 1970,49, 173–183.

    CAS  PubMed  Google Scholar 

  7. ALPER M.H. — Toxicity of local anesthetics.N. Engl. J. Med., 1976,295, 1432–1433.

    Article  CAS  PubMed  Google Scholar 

  8. ALTMAN R.S., SMITH-COGGINS R., AMPEL L.L. — Local anesthetics.Ann. Emerg. Med., 1985,14, 1209–1217.

    Article  CAS  PubMed  Google Scholar 

  9. A.M.A. Council on Drugs. — A.M.A. Drug evaluations 5th edition — American Medical Association, Chicago, 1983.

  10. AMITAI Y., WHITESELL L., LOVEJOY F.H. — Death following accidental lidocaine overdose in a child.N. Engl. J. Med., 1986,314, 182–183.

    CAS  PubMed  Google Scholar 

  11. BARKER S.J., TREMPER K.K., HYATT J. — Effects of methemoglobinemia on pulse oximetry and mixed venous oximetry.Anesthesiology, 1989,70, 112–117.

    Article  CAS  PubMed  Google Scholar 

  12. BEAVIS A.K., LABROOY S., MISIEWICZ J.J. — Evaluation of one visit endoscopy clinic for patients with dyspepsia.Br. Med. J., 1979,1, 387–389.

    Google Scholar 

  13. BELL G.D. — Review article: premedication and intravenous sedation for upper gastrointestinal endoscopy.Aliment. Pharmacol. Therapy, 1990,4, 103–122.

    Article  CAS  Google Scholar 

  14. BENOWITZ N.L. — Clinical Pharmacokinetics of Lignocaine.Clin. Pharmacokinetics, 1978,3, 177–201.

    Article  CAS  Google Scholar 

  15. BUSIS S.N., ARONOW W.S. — Tinnitus and lidocaine therapy.JAMA, 1985,253, 2119.

    Article  Google Scholar 

  16. CANTOR D.S., BALDRIDGE E.T. — Premedication with meperidine and diazepam for upper gastrointestinal endoscopy precludes the need for topical anesthesia.Gastrointest. Endosc., 1986,32, 339–341.

    Article  CAS  PubMed  Google Scholar 

  17. CARABELLI A. — Use of Pontocaine in Subposologie quantities for bronchoscopy and bronchography.Anesthesiology, 1952,13, 169–183.

    Article  CAS  PubMed  Google Scholar 

  18. COUSINS M.J., BRIDENBAUGH P.O. — Neural Blockade in Clinical Anesthesia and Management of Pain. Philadelphia Lippincott 1980.

  19. COVINO B.G. — Local anesthesia (first of two parts).N. Engl. J. Med., 1972,286, 975–982.

    Article  CAS  PubMed  Google Scholar 

  20. COVINO B.G. — Local anesthesia (second of two parts).N. Engl. J. Med., 1972,286, 1035–1042.

    Article  CAS  PubMed  Google Scholar 

  21. DAVIS R.E., GRAHAM D.Y. — Endoscopic complications — the Texas experience.Gastrointest. Endosc., 1979,25, 146–149.

    Article  CAS  PubMed  Google Scholar 

  22. DE JONG R.H. — Toxic effects of local anesthetics.JAMA, 1978,239, 1166–1168.

    Article  PubMed  Google Scholar 

  23. Epidemiology of Contact Dermatitis in North America, 1972.Arch. Dermatol., 1973,108, 537–540.

    Google Scholar 

  24. EYRES R.L., BISHOP W., OPPENHEIM R.C. et al. — Plasma lidocaine concentrations following topical laryngeal application.Anesth. Intern. Care, 1983,11, 23–26.

    CAS  Google Scholar 

  25. FISHER A.A. — Contact Dermatitis, Questions and Answers.Cutis, 1982,29, 16–19.

    Google Scholar 

  26. FRUNCILLO R.J., GIBBONS W., BOWMAN S.M. — C.N.S. toxicity after ingestion of topical lidocaine.N. Engl. J. Med., 1982,306, 426–427.

    CAS  PubMed  Google Scholar 

  27. GORDON M.J., MAYES G.R., MEYER G.W. — Topical lidocaine in preendoscopic medication.Gastroenterol., 1976,71, 564–569.

    CAS  Google Scholar 

  28. GREENBLATT D.J., BENJAMIN D.M., WILLIS C.R., HARMATZ J.S., ZINNY M.A. — Lidocaine plasma concentrations following administration of intraoral lidocaine solution.Arch. Otolaryngol., 1985,111, 298–300.

    Article  CAS  PubMed  Google Scholar 

  29. GRUM D.F., RICE T.W. — Methemoglobinemia from topical benzocaine.Cleve. Clin. J. Med., 1990,57, 357–359.

    Article  CAS  PubMed  Google Scholar 

  30. HEDENBRO J.L., LINDBLOM A.L. — Patient attitudes to sedation for diagnostic upper endoscopy.Scand. J. Gastroenterol., 1991,26, 1115–1120.

    Article  CAS  PubMed  Google Scholar 

  31. HEDENBRO J.L., ABERG T. — Oral sedation for diagnostic upper endoscopy.Endoscopy, 1991,23, 8–10.

    Article  CAS  PubMed  Google Scholar 

  32. HEDENBRO J.L., EKELUNG M., JANSSON O., LINDBLOM A. — A randomized double-blind, placebo-controlled study to evaluate topical anesthesia of the pharynx in upper gastrointestinal endoscopy.Endoscopy, 1992,24, 585–587.

    Article  CAS  PubMed  Google Scholar 

  33. HOWARD J.J., MOHSENIFAR Z., SIMONS S.M. — Adult respiratory distress syndrome following administration of lidocaine.Chest, 1982,81, 644–645.

    Article  CAS  PubMed  Google Scholar 

  34. INCAUDO G., SCHATZ M., PATTERSON R., ROSENBERG M., YAMAMOTO F., HAMBURGER R. — Administration of local anesthetics to patients with a history of prior adverse reaction.J. Allergy Clin. Immunol., 1978,61, 339–345.

    Article  CAS  PubMed  Google Scholar 

  35. JOHNSON W.T., DESTIGTER T. — Hypersensitivity to procaine, tetracaine, mepivacaine and methylparaben: report of a case.JAMA, 1983,106, 53–56.

    Article  CAS  Google Scholar 

  36. JONES F.A., DOLL R., FLETCHER C. et al. — The risks of gastroscopy: a survey of 49,000 examinations.Lancet, 1951,1, 647–651.

    PubMed  Google Scholar 

  37. KELLET P.B., COPELAND C.S. — Methemoglobinemia associated with benzocaine-containing lubricant.Anesthesiology, 1983,59, 463–464.

    Article  Google Scholar 

  38. KOTLER R.L., HANSEN-FLASCHEN J., CASEY M.P. — Severe methaemoglobinaemia after flexible fiberoptic bronchoscopy.Thorax, 1989,44, 234–235.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. LABEDZKI L., OCHS H.R., ABERNETHY D.R., GREENBLATT D.J. — Potentially toxic serum lidocaine concentrations following spray anesthesia for bronchoscopy.Klin. Wochenschr., 1983,61, 379–380.

    Article  CAS  PubMed  Google Scholar 

  40. LACHTER J., JACOBS R., LAVY A., WEISLER A., SUISSA A., ENAT R., EIDELMAN S. — Topical pharyngeal anesthesia for easing endoscopy, a double-blind, randomized, placebo-controlled study.Gastrointest. Endosc., 1990,36, 19–21.

    Article  CAS  PubMed  Google Scholar 

  41. LAMPE K.F. — Allergic hypersensitivity to local anesthetics.JAMA, 1982,247, 2155.

    Google Scholar 

  42. LIE R.L., VERMEER B.J., EDELBROEK P.M. — Severe lidocaine intoxication by cutaneous absorption.J. Am. Acad. Dermatol., 1990,23, 1026–1028.

    Article  CAS  PubMed  Google Scholar 

  43. LIU P., FELDMAN H.S., COVINO B.M., GIASI R., COVINO B.G. — Acute cardiovascular toxicity of intravenous amide local anesthetics in anesthetized ventilated dogs.Anesth. Analg., 1982,61, 317–322.

    CAS  PubMed  Google Scholar 

  44. LIU P., FELDMAN H.S., COVINO B.M., GIASI R., COVINO B.G. — Acute cardiovascular toxicity of procaine, chlorprocaine and tetracaine in anesthetized ventilated dogs.Reg. Anest., 1982,7, 14–19.

    CAS  Google Scholar 

  45. LIU P., FELDMAN H.S., GIASI R., PATTERSON M.K., COVINO B.G. — Comparative C.N.S. toxicity of lidocaine, etidocaine, bupivacaine and tetracaine in awake dogs following rapid intravenous administration.Anesth. Analg., 1983,62, 375–379.

    Article  CAS  PubMed  Google Scholar 

  46. LYNAS R.F. — A suspected allergic reaction to lidocaine.Anesthesiology, 1969,31, 380–382.

    Article  CAS  PubMed  Google Scholar 

  47. McALPINE L.G., THOMSON N.C. — Lidocaine-induced bronchoconstriction in asthmatic patients, relation to histamine airway responsiveness and effect of preservative.Chest, 1989,96, 1012–1015.

    Article  CAS  PubMed  Google Scholar 

  48. MANDELSTAM P., SUGAWA C., SILVIS S.E., NEBEL O.T., ROGERS B.H.G. — Complications associated with esophagogastroduodenoscopy and with esophageal dilation.Gastrointest. Endosc., 1976,23, 16–19.

    Article  CAS  PubMed  Google Scholar 

  49. MANSSON I., SANDBERG N. — Effects of surface anesthesia on deglutition in man.The Laryngoscope, 1973, 427–437.

  50. MATHER LE., COUSINS M.J. — Local anaesthetics and their current clinical use.Drugs, 1979,18, 185–205.

    Article  CAS  PubMed  Google Scholar 

  51. MOFENSON H.C. — Lidocaine toxicity from topical mucosal application with a review of the clinical pharmacology of lidocaine.Clin. Ped., 1983,22, 190–192.

    Article  CAS  Google Scholar 

  52. NELIS G.F. — Preparation for endoscopy.Lancet, 1980,2, 861–862.

    Article  CAS  PubMed  Google Scholar 

  53. PALMER E.D., WIRTS C.W. — Survey of gastroscopic and esophagoscopic accidents.JAMA, 1957,164, 2012–2015.

    Article  CAS  Google Scholar 

  54. PATEL D., CHOPRA S., BERMAN M.D. — Serious systemic toxicity resulting from use of tetracaine for pharyngeal anesthesia in upper endoscopic procedures.Dig. Dis. Sci., 1989,34, 882–884.

    Article  CAS  PubMed  Google Scholar 

  55. PROMISLOFF R.A., DUPONT D.C. — Death from A.R.D.S and cardiovascular collapse following lidocaine administration (letter).Chest, 1983,3, 585.

    Article  Google Scholar 

  56. PROUT B.J., METREWELI C. — Pulmonary aspiration after fibre-endoscopy of the upper gastrointestinal tract.Br. Med. J., 1972,4, 269–271.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  57. ROSIVACK R.G., KOENIGSBERG S.R., MAXWELL K.C. — An analysis of the effectiveness of two topical anesthetics.Anesth. Prog., 1990,37, 290–292.

    CAS  PubMed  PubMed Central  Google Scholar 

  58. ROSS W.A. — Premedication for upper gastrointestinal endoscopy.Gastrointest. Endosc., 1989,35, 120–126.

    Article  CAS  PubMed  Google Scholar 

  59. RUBIN M., KULLY B. — Speed of administration as related to toxicity of certain topical anesthetics.Ann. Otol. Rhin. & Laryng., 1951,60, 627–630.

    Article  CAS  Google Scholar 

  60. SCHILLER K.F.R., COTTON P.B., SALMON P.R. — The hazards of digestive fibre endoscopy. A survey of British experience.Gut, 1972,13, 1027.

    CAS  PubMed  Google Scholar 

  61. SCOTT D.B. — Evaluation of the toxicity of local anesthetics agents in man.Br. J. Anaesth., 1975,47, 56–61.

    Article  CAS  PubMed  Google Scholar 

  62. SCOTT D.B. — Toxic effects of local anaesthetic agents on the central nervous system.Br. J. Anaesth., 1986,58, 732–735.

    Article  CAS  PubMed  Google Scholar 

  63. SEVERINGHAUS J.W., XU F., SPELLMAN M.J. — Benzocaine and methemoglobin: recommended actions.Anesthesiology, 1991,74, 385–386.

    Article  CAS  PubMed  Google Scholar 

  64. SHIPLEY R.H., BUTT J.H., FARBRY J.E., HORWITZ B. — Psychological preparation for endoscopy. Physiological and behavioral changes in patients with differing coping styles for stress.Gastrointest. Endosc., 1977,24, 9–13.

    Article  CAS  PubMed  Google Scholar 

  65. SMITH M.R., BELL G.D. — Routine oxygen during endoscopy? An editorial review.Endoscopy, 1993,25, 298–300.

    Article  CAS  PubMed  Google Scholar 

  66. SPARBURG M., KNUDSON K. — Is local anesthesia necessary in fiberoptic esophagogastroscopy?New Series, 1967,12, 1131–1134.

    Google Scholar 

  67. STADLER F.X., HEROLD R., KISTLER H.J. — Lidocain-intoxikation, Beobachtung bei 5 Patienten mit letalem (2 Patienten) und reversiblem Verlauf.Schweiz. Med. Wochenschr., 1979,109, 1941–1945.

    CAS  PubMed  Google Scholar 

  68. TAYLOR P.A., COTTON P.B., TOWEY R.M., GENT A.E. — Pulmonary complications after oesophagogastroscopy using diazepam.Br. Med. J., 1972,1, 666.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  69. TUCKER H.M., AL HADDAD S. — Topical anesthesia for peroral endoscopy.Ear, Nose, Throat. J., 1991,70, 494–496.

    CAS  Google Scholar 

  70. TYTGAT G.N.J. — Endoscopy of the oesophagus.Curr. Opin. Gastroenterol., 1990,6, 15–25.

    Article  Google Scholar 

  71. VESSELY M.B., ZITSCH R.P. — Topical anesthetic induced methemoglobinemia, a case report and review of the literature.Otolaryngol. Head. Neck. Surg., 1993,108, 763–767.

    Article  CAS  PubMed  Google Scholar 

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  1. Ph. Bohon

    Present address: Service de gastroentérologie, U.C.L.-Cliniques Universitaires Saint-Luc, avenue Hippocrate 10, 1200, Bruxelles, Belgique

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  1. Service de gastroentérologie, U.C.L.-Cliniques Universitaires Saint-Luc, avenue Hippocrate 10, 1200, Bruxelles, Belgique

    P. Mainguet & A. Geubel

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Bohon, P., Mainguet, P. & Geubel, A. Complications de l’anesthésie topique du pharynx avant endoscopie digestive supérieure. Acta Endosc 24, 271–283 (1994). https://doi.org/10.1007/BF02969608

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