Skip to main content

Advertisement

Log in

Diagnostic différentiel entre infection et inflammation dans les maladies inflammatoires de l’intestin

Diagnosis of infection versus inflammation in inflammatory bowel disease

Diagnóstico diferencial entre infección e inflamación en las enfermedades inflamatorias intestinales

  • Published:
Acta Endoscopica

Résumé

Le diagnostic différentiel entre processus infectieux et inflammatoire est souvent difficile à l’apparition d’une diarrhée. Outre le rôle étiopathogénique possible de certains agents infectieux dans les maladies inflammatoires chroniques du tube digestif, une surinfection peut conduire à des erreurs diagnostiques au cours d’une poussée inflammatoire. La clinique, la biologie et les techniques d’imagerie sont extrêmement utiles dans le diagnostic différentiel. Le contenu endoluminal et les lésions limitées à la muqueuse seront précisés par les méthodes de laboratoire, l’endoscopie et son support histologique et/ou l’étude radiologique barytée.

En cas de suspicion de fistule ou d’abcès, l’échographie représente la meilleure technique d’imagerie de première intention, bien que la tomodensitométrie reste la méthode la plus sensible (95 %).

Les signes cliniques autant que la biologie, la radiologie et la médecine nucléaire seront de grande utilité en cas de complication systémique, qu’elle soit d’origine infectieuse ou inflammatoire.

Summary

Differential diagnosis between inflammation and infectious processes is often difficult at the onset of a diarrheal syndrom. In addition of the possible etiopathogenic role of some infectious agents in IBD, superinfection may lead to misdiagnosis in case of active IBD. Several clinical, biological and morphological features are available and may be strongly helpful for the differential diagnosis. The intraluminal content and the lesions limited to the mucosa should be distinguished by laboratory methods, endoscopy with histological support and/or radiological barium study.

When fistulae or abscesses are suspected, sonography represents the best imaging modality for the initial investigation, although computed tomography remains the most accurate procedure with a 95 % sensitivity.

Clinical signs as well as biological, radiological or nuclear techniques should be of great interest in case of systemic infectious or inflammatory complications.

Resumen

En una diarrea, el diagnóstico diferencial entre un proceso infaccioso o inflamatorio es generalmente difícil. Además el posible papel etiopatogénico de ciertos agentes infecciosos en las enfermedades inflamatorias crónicas del tubo digestivo, una sobre-infección, puede inducir a errores diagnósticos en el curso de un acceso inflamatorio. La clínica, la biología y las téchnicas imagenológicas son extremadamente útiles en el diagnóstico diferencial. El contenido endoluminal y las lesiones limitadas a la mucosa serán precisadas por téchnicas de laboratorio, la endoscopio y su sporte histológico y/o el estudio bardado radiológico.

En caso de sospecha de fístula o de abceso, la ecografía representa la mejor téchnica imagenológica de primera instancia aunque la escanografía continúa siendo el método más sensible (95 %).

Los signos clínicos así como la biología, la radiología y la medicina nuclear serán de gran utilidad en caso de complicación sistémica, cualquiera que sea su origen infeccioso o inflamatorio.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Références

  1. BELSHEIM M., DARWICH R.Z., WATSON W.C., SCHIEREN B. — Bacterial L-form isolation from inflammatory bowel disease patients.Gastroenterology, 1983, 85, 364–368.

    PubMed  CAS  Google Scholar 

  2. BLAAUWGEERS H.J.L.G., MULDER C.J.J., DAS P.K., HAAGSMA J., TYTGAT G.N.J. — Crohn’s disease, a micobacterial aetiology?Eur. J. Gastr. Hepat., 1990, 2, 4, 237–240.

    Google Scholar 

  3. CASOLA G., VANSONNENBERG E., NEFF C.C., SABA R.M., WITHERS C. EMARINE C.W. — Abscessess in Crohn’s disease: percutaneous drainage.Radiology, 1987, 163, 1, 19–22.

    PubMed  CAS  Google Scholar 

  4. DALZIEL T.K. — Chronic interstitial enteritis.Br. Med. J., 1913, 11, 1068–1070.

    Google Scholar 

  5. ENGELHOLM L., DE TOEUF J., ZALCMAN M., JEANMART J. — Computerized tomography in Crohn’s disease.Acta Gastroenterol. Belg., 1987, 50, 5, 538–552.

    PubMed  CAS  Google Scholar 

  6. GITNICK G., COLLINS J., BEAMAN B., BROOKS D., ARTHUR M. — Mycobacteria in Crohn’s disease.Gastroenterology, 1985, 88, 1396 (Abstr).

    Google Scholar 

  7. HAMPSON S.J., MCFADDEN J.J., HERMON-TAYLOR J. — Mycobacteria and Crohn’s disease.Gut, 1988, 29, 1017–1019.

    Article  PubMed  CAS  Google Scholar 

  8. HAMPSON S.J., PARKER M.C., SAVERYMUTHU S.H., MCFADDEN J.J. TAYLOR J.H. — Results of quadruple antimycobacterial chemotherapy in 17 Crohn’s disease patients completing six months treatment.Gastroenterology, 1988, 94, A 170.

    Google Scholar 

  9. JEWKES J., LARSON H.E., PRICE A.B., SAUNDERSON P.J., DAVIEW H.A. — Aetiology of acute diarrhea in adult.Gut, 1981, 22, 388.

    Article  PubMed  CAS  Google Scholar 

  10. KOBAYASHI K., BLASER M.J., BROWN W.R. — Immunohistochemical examination for mycobacteria in intestinal tissues from patients with Crohn’s disease.Gastroenterology, 1989, 96, 1009–1015.

    PubMed  CAS  Google Scholar 

  11. KUMAR N.B., NOSTRANT T.T., APPELMAN H.D. — The histopathologic spectrum of acute self-limited colitis (acute infectious-type colitis).Am. J. Surg. Path., 1982, 6, 523.

    Article  PubMed  CAS  Google Scholar 

  12. LUBAT E., BALTHAZAR E.J. — The current role of computerized tomography in inflammatory disease of the bowel.Am. J. Gastroenterol., 1988, 83, 2, 107–113.

    PubMed  CAS  Google Scholar 

  13. NOSTRANT T.T., KUMAR N.B., APPELMAN H.D. — Histopathology differentiates acute self-limited colitis from ulcerative colitis.Gastroenterology, 1987, 92, 318.

    PubMed  CAS  Google Scholar 

  14. PARENT K., MITCHELL P.D. — Bacterial variants: etiological agent in Crohn’s disease?Gastroenterology, 1976, 71, 365–368.

    PubMed  CAS  Google Scholar 

  15. PARENT K., MITCHELL P.D. — Cell-wall defective variants of Pseudomonas-like (group Va) bacteria in Crohn’s Disease.Gastroenterology, 1978, 75, 368–372.

    PubMed  CAS  Google Scholar 

  16. PRICE A.B., JEWKES J., SANDERSON P.J. — Acute diarrhea. Campylobacter colitis and the role of rectal biopsy.J. Clin. Pathol., 1979, 32, 990.

    Article  PubMed  CAS  Google Scholar 

  17. SCHMUTZ G., RIDEREAU C., BEIGELMAN C., BAUMANN R., JOUIN H., SADNI M. — Sonographic contribution in Crohn’s disease.Acta Gastroenterol. Belg., 1987, 50, 5, 532–537.

    PubMed  CAS  Google Scholar 

  18. SHAFFER J.L., HUGHES S., LINAKER B.D., BAKER R.D., TURNBERG L.A. — Controlled trial of rifampicin and ethambutol in Crohn’s disease.Gut, 1984, 25, 203–205.

    Article  PubMed  CAS  Google Scholar 

  19. SURAWICZ C.M., BELIC L. — Rectal biopsy helps to distinguish acute self-limited colitis from idiopathic inflammatory bowel disease.Gastroenterology, 1984, 86, 104–114.

    PubMed  CAS  Google Scholar 

  20. TEDESCO F.J., HARDIN R.D., HARPER R.N., EDWARDS B.H. — Infectious colitis endoscopically simulating inflammatory bowel disease.Gastrointest. Endosc., 1983, 29, 195–197.

    Article  PubMed  CAS  Google Scholar 

  21. THAYER W.R., COUTU J.A., CHIODINI R.G., VAN KRUNINGEN H.J., MERKAL R. — Possible role of mycobacteria in inflammatory bowel disease. II. Mycobacterial antibodies in Crohn’s disease.Dig. Dis. Sci., 1984, 29, 1080–1085.

    Article  PubMed  Google Scholar 

  22. TYTGAT G.N.J., MULDER C.C.J., — The aetiology of Crohn’s Disease Intern.J. Colorectal Disease, 1986, 1, 3, 188–192.

    Article  CAS  Google Scholar 

  23. WILHELM J.P., BRESSON A., CLAUDON M., REGENT D., CHAMPIGNEULLE B., BIGARD M.A., GAUCHER P. — Study of the small bowel and mesentery in Crohn’s disease: comparison of ultrasonics, x-ray computed tomography and small bowel transit in 18 patients.Ann. Gastroenterol. Hépatol., 1988, 24, 2, 49–54.

    CAS  Google Scholar 

  24. YOSHIMURA H.H., ESTES M.K., GARHAM D.Y. — Search for evidence of a viral aetiology for inflammatory bowel disease.Gut, 1984, 25, 347–355.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

About this article

Cite this article

Reuck, M.D. Diagnostic différentiel entre infection et inflammation dans les maladies inflammatoires de l’intestin. Acta Endosc 21, 275–282 (1991). https://doi.org/10.1007/BF02968716

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02968716

Mots-clés

Key-words

Palabras claves

Navigation