Résumé
Les adénomes porteurs d’un carcinome invasif constituent la majorité des cancers colo-rectaux au début. Au cours des douze dernières années, 3 600 polypes ont été réséqués par voie coloscopique chez 1 936 patients.
69 adénomes porteurs d’un carcinome invasif ont été décelés chez 69 patients.
Les paramètres histopathologiques rendent possible la distinction entre les cas à haut et à faible risque de métastases lymphatiques.
Une comparaison a été établie entre la polypectomie endoscopique seule chez les patients à faible risque, et la chirurgie chez les patients à haut risque.
52 cas à risque faible ont été traités par polypectomie endoscopique sans chirurgie ; 17 malades ont subi une intervention chirurgicale.
Aucune métastase à distance n’a été objectivée dans le groupe polypectomisé ; des ganglions lymphatiques métastatiques ont été trouvés après intervention chez 40 % des patients à haut risque.
Ces résultats confirment l’attitude thérapeutique adoptée chez les patients à faible risque ; par contre chez les patients à haut risque, une évaluation histo-pathologique soigneuse est indispensable.
Summary
Adenomas containing invasive carcinoma are the majority of early colorectal cancers.
In the last 12 years about 3 600 polyps have been removed by colonoscopic polypectomy in 1936 patients.
69 adenomas containing invasive carcinoma have been found in 69 patients.
Pathological parameters make it possible to distinguish between high and low risk cases of limphnode metastases.
Endoscopic polypectomy alone in low risk patients has been compared to major surgery in high risk cases.
52 low risk cases have been treated only by E.P. ; 17 patients underwent surgery.
No distant metastases have been so far evidenced in the polypectomy group ; limphnode metastases have been found at operation in 40 % of high risk cases.
The observed results confirm the value of the actual therapeutic policy in low risk patients ; in high risk cases a careful pathological evaluation is mandatory.
References
HERMANEK P. - Colorectal polyps and polyposis.Proctology, 1979,2, 8–16.
HERMANEK P. - Polypectomy in the colorectum: histological and oncological aspects.Endoscopy, 1983,15, 158–161.
KONISHI F., MORSON B.C. - Pathology of colorectal adenomas: a colonoscopic survey.J. Clin. Pathol., 1982,35, 830–841.
ROSSINI F.P., FERRARI A., SPANDRE M., COVERLIZZA S. - Colonoscopic polypectomy in diagnosis and management of cancerous adenomas. An individual and multicentric experience.Endoscopy, 1982,14, 124–127.
ROSSINI F.P., FERRARI A., SPANDRE M., CAVALLERO M., RISIO M., COVERLIZZA S. - Diagnosis and management of adenomas with invasive carcinoma: an Italian experience. In :Adenomas and adenomas containing carcinoma of the large bowel, Fenoglio-Preiser CM., Rossini F.P., New York, Raven Press, 1985, 83–102.
MUTO T., BUSSEY H.J.R., MORSON B.C. - The evolution of cancer of the colon and rectum.Cancer, 197536, 2251–2270.
DESCHNER E.E. - Adenomas. Preneoplastic events, growth characteristic and development.Pathol. Annu., 1983,13, 205–219.
FENOGLIO CM., PASCAL R.R. - Colorectal adenomas and cancer, Pathologic relationships.Cancer, 1982,50, 2600–2608.
FENOGLIO-PREISER CM. - Polyps and the subsequent development of carcinoma of the colon and rectum. Definitions and hints on tissue handling. In:Adenomas and adenomas containing carcinoma of the large bowel, Fenoglio-Preiser CM., Rossini F.P., New York, Raven Press, 1985, 15–29.
ROSSINI F.P., FERRARI A., SPANDRE M., CAVALLERO M., GEMME C. - Complications of colorectal diagnostic and surgical endoscopy.Surgical Endoscopy (in press).
ROSSINI F.P., FERRARI A., SPANDRE M., CAVALLERO M., GEMME C, SCEVOLA F., COVERLIZZA S. -Polipectomia endoscopia e adenomi del grosso intestino: 12 anni di esperienza. Atti VII Congresso Naz. AIGO, 1984, 243-248.
MORSON B.C., WHITEWAY J.E., JONES E.A., MACRAE F.A., WILLIAMS C.B.- Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy.Gut, 1984,25, 437–444.
MORSON B.C., BUSSEY H.J.R. - Magnitude of risk for cancer in patients with colorectal adenomas.Br. J. Surg., 1985, suppl., 523-528.
MORSON B.C., SOBIN L.H. -Histological Typing of Intestinal Tumours. W.H.O., Genova, 1976.
FENOGLIO-PREISER CM. - The distribution of large intestinal lymphatics: relationship to risk of metastasis from carcinomas of the large intestine. In:Adenomas and adenomas containing carcinoma of the large bowel, Fenoglio-Preiser C.M., Rossini F.P., New York, Raven Press, 1985, 7–14.
MORSON B.C., DAWSON I.M.P. -Gastrointestinal pathology, 2nd ed. Ed. Oxford: Backwell Scientific Publications, 1979, 648.
RUSSEL A.H., TONG D., DAWSON L.E., WISBECK W. - Adenocarcinoma of the proximal colon.Cancer, 1984,53, 360–367.
HAVELAAR I.J., SUGARBAKER P.H., VERMESS M., MILLER D.L. - Rate of growth of intraabdominal metastases from colorectal cancer.Cancer, 1984,54, 163–171.
CHRISTIE J.P. - Malignant colon polyps: cure by colonoscopy or colectomy ?Am. J. Gastroenterol., 198479 543–547.
Forza operativa nazionale sul carcinoma del tratto digerente (F.O.N.C.A.D.) -I tumori del colon-retto. Milano, I.N.T., 1984.
LANGER J.C., COHEN Z., TAYLOR B.R., STAFFORD S, JEEJEEBHOLY K.N., CULLEN J.B. - Management of patients with polyps containing malignancy removed by colonoscopic polypectomy.Dis. Colon Rectum, 1984,27, 6–9.
KODAIRA S., TERAMOTO T., ONO S. - Lymph node metastase from carcinomas developing in pedunculated and semipeduncalutad colorectal adenomas.Aust. NZ J. Surg., 1981,51, 429–433.
M.V. - When is endoscopic polypectomy adequate therapy for colonic polyps containing invasive carcinoma ?Gastroenterology, 1986,91, 419–427.
COLACCHIO T.A., FORDE K.A., SCANTLEBURY V.P. - Endoscopie polypectomy: inadequate treatment for invasive colorectal carcinoma.Ann. Surg., 1981,194, 704–707.
COUTSOFTIDES T., SIVAK M.V., BENJAMIN S.P., JAGELMAN D. - Colonoscopy and the management of polyps containing invasive carcinoma.Ann. Surg., 1978,188, 638–641.
MUTO T., KAMINA J., SWADA T. et al. - Colonoscopic polypectomy in diagnosis and treatment of early carcinoma of the large intestine.Dis. Colon Rectum, 1980,23, 68–75.
LABGER J.C., COHEN Z., TAYLOR B.R., STAFFORD S., JEEJEEBHOLY K.N., CULLEN J.B. - Management of patients with polyps containing malignancy removed by colonoscopic polypectomy.Dis. Colon Rectum, 1984,27, 6–9.
WILCOX J.M., ANDERSON P.B., COLACCHIO T.A. - Early invasive carcinoma in colonie polyps.Cancer, 1986,57, 160–171.
DECOSSE J.J. - Malignant colorectal polyp. Leading article.Gut, 1984,25, 433–436.
COOPER H.S. - Surgical pathology of endoscopically removed malignant polyps of the colon and rectum.Am. J. Surg. Pathol., 1983,7, 613–622.
Author information
Authors and Affiliations
About this article
Cite this article
Rossini, F.P., Ferrari, A., Coverlizza, S. et al. Adénomes bénins et adénomes dégénérés du côlon. Expérience de 12 ans de polypectomie endoscopique. Acta Endosc 17, 137–143 (1987). https://doi.org/10.1007/BF02968599
Issue Date:
DOI: https://doi.org/10.1007/BF02968599