Abstract
We report a case of fibromatosis clinically suggestive of breast cancer, in which cancer treatment was prevented by fine needle aspiration (FNA) cytology. The patient was a 46-year-old Japanese woman who presented with nipple retraction of the left breast. Mammography demonstrated thickened nipple skin and an ill-defined, fairly dense tumor retracting the nipple. Ultrasonography showed an irregular hypoechoic tumor with a thick boundary echo and back echo attenuation. FNA was performed, and the aspirates consisted of isolated pleomorphic spindle cells showing large nuclei with fine chromatin and lacy cytoplasm, and papillary epithelial and myoepithelial cells. Thus an epithelial malignant tumor was ruled out. In this case, in which carcinoma was clinically strongly suspected and in which aspirates consisted of isolated pleomorphic spindle cells, fibromatosis should be considered to avoid unnecessary radical surgery.
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Abbreviations
- FNA:
-
Fine needle aspiration
References
Rosen PP: Benign mesenchymal neoplasms. In: Rosen PP eds, Rosen’s Breast Pathology, 2nd ed, Lippincott Williams & Wilkins Co, Philadelphia, pp749–757, 2001.
Azzopardi JG, Ahmed A, Millis RR: Miscellaneous entities. In: Bennington JL eds, Major problems in pathology, W.B.Saunders Co, London, pp395, 1979.
Cameron CT, Adair FE: The clinical feature and diagnosis of the common breast tumors.Med J Aust 2: 651–654, 1965.
Hashimoto K, Itoh H, Okamura R,et al: Aggressive fibromatosis infiltrating breast Report of case and review of literature.Kobe J Med Sci 32: 59–70, 1986.
Mitsuyama S, Katsumoto F, Sakata M,et al: Fibromatosis of the Breast: A case report.Geka 51: 297–299, 1989 (in Japanese).
Tamura H, Ikeda H, Enomoto H,et al: fibromatosis of the breast; report of two cases.Jpn J Breast Cancer 9: 587–592, 1994 (in Japanese with English summary).
Koibuchi Y, Iino Y, Oyama T,et al: Fibromatosis of the Breast: A case report.Jpn J Clin Oncol 25: 16–19, 1995.
Kiyono T, Okuda K, Nishiwaki M,et al: Fibromatosis of the Breast: A case report.Jpn J Breast Cancer 14: 280–283, 1999.
Nagaoka H, Higashi Y, Suematsu K,et al: Fibromatosis of the breast: A case report.Breast Cancer 4: 121–125, 1997.
Fujimoto K,et al: A case of fibromatosis of the breast.Jpn J Med Ultrasonics 21: 165–168, 1994.
Kimura H,et al: A case report of fibromatosis of the breast.Yokohama Igaku 46: 89–93, 1995.
Osaki H,et al: A case of fibromatosis of the breast.J Jpn Soc Clin Cytol 37: 318–322, 1998.
Wargotz ES, Norris HJ, Austin RM,et al: Fibromatosis of the breast: a clinical and pathological study of 28 cases.Am J Surg Pathol 11: 38–45, 1987.
Cederlund CG, Gutavsson S, Linell F,et al: Fibromatosis of the breast mimicking carcinoma at mam-mography.Br J Radiol 57: 98–101, 1984.
Thomas T, Lorino C, Ferrara JJ: Fibromatosis of the breast: A casereport and literature review.J Surg Oncol 35: 70–74, 1987.
Leibman AJ, Kossoff MB: Sonographyic features of fibromatosis of the breast.J Ultrasound Med 10: 43–45, 1991.
Chhieng DC, Cangiarella JF, Waisman J,et al: Fineneedle aspiration cytology of spindle cell lesions of the breast.Cancer 87: 359–371, 1999.
Chhieng DC, Cohen JM: Fine needle aspiration (FNA) cytology of mammary fibromatosis: a case report and review of literature.Cytopathology 10: 354–359, 1999.
Kalbhen CL, Cooper RA, Candel AG: Mammographic and stereotactic core biopsy findings in fibromatosis of the breast: case report.Can Assoc of Radiol J 49: 229–231, 1998.
Burrell HC, Sibbering DM, Wilson ARM: Case report: Fibromatosis of the breast in a male patient.Br J Radiol 68: 1128–1129, 1995.
Shuler FJ, Cronin EB, Ricci AR,et al: Fibromatosis of the breast diagnosed by stereotactic core biopsy.AJR 168: 846–847, 1997.
Rosen PP, Ernsberger D: mammary fibromatosis. A benign spindle cell tumor with significant risk for local recurrence.Cancer 63: 1363–1369, 1989.
Gump FE, Sternschein MJ, Wolf M,et al: Fibromatosis of the breast.Surg Gynecol Obstet 153: 57–60, 1981.
Bauernhofer T, Stoger H Schmid Met al: Sequential treatment of recurrent mesenteric desmoid tumor.Cancer 77: 1061–1065, 1996.
Sportiiello DJ, Hoogerland DL: A recurrent pelvic desmoid tumor successfully treated with tamoxifen.Cancer 67: 1443–1446, 1991.
Kinzbrunner B, Ritter S, Domingo J,et al: remission of rapidly growing desmoid tumors after tamoxifen therapy.Cancer 52: 2201–2204, 1983.
Sauven P: Musculo-aponeurotic fibromatosis treated by surgery and testolactone.J R Soc Med 75: 281–283, 1982.
Reitamo JJ, Scheinin TM, Hayry P,et al: The desmoid tumor; New aspects in the cause, pathogenesis and treatment of the desmoid tumor.Amj Surg 151: 230–237, 1986.
Lim, CL, Walker MJ, Mehta RR,et al: Estrogen and antiestrogen binding sites in desmoid tumors.Eur J Cancer Clin Oncol 22: 583–587, 1986.
Rosen PP, Oberman HA: Benign mesenchymal tumors. In: Rosen PP eds, Atlas of tumor pathology, Third series Fascicle 7 Tumors of the mammary gland, Universities associated for research and education in pathology, INC., Maryland, pp306–312, 1993.
Koshima I, Inagawa K, Yamamoto M,et al: New microsurgical breast reconstruction using free paraumbilical perforator adiposal flaps.Plast Reconstr Surg 106: 61–65, 2000.
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Reprint requests to Satoko Nakano, Department of Surgery, Kawaguchi Municipal Medical Center, 180 Nishiaraijuku Kawaguchi-shi, Saitama 333–0833, Japan.
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Satoko, N., Masahiko, O., Takamitsu, H. et al. Fibromatosis of the breast: A case report. Breast Cancer 9, 179–183 (2002). https://doi.org/10.1007/BF02967585
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DOI: https://doi.org/10.1007/BF02967585