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Three-dimensional mr imaging of mammographically detected suspicious microcalcifications

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Abstract

Background

The purpose of this study was to evaluate the diagnostic value and clinical significance of three-dimensional MR imaging of the breast in patients with mammographically detected suspicious microcalcifications.

Methods

Forty patients with suspicious microcalcifications on mammography were evaluated with three-dimensional MR imaging. MR findings were grouped mainly by distribution of abnormal enhancement (linear, focal-clumped, segmental-clumped, segmental-stippled and diffuse-stippled). These findings were compared with the mammography findings according to the criteria of the Breast Imaging Reporting and Data System (BI-RADS) and histopathologic data.

Results

Twenty patients had proven malignancies, most frequently ductal carcinomain situ. For all the cases, linear (100%) and segmental-clumped type (100%) enhancement on MR imaging showed a significantly higher risk for malignancy. Diffuse stippled type (7%) and no enhancement (0%) on MR imaging indicated the lowest possibility of malignancy. 3D-MR imaging showed a sensitivity of 90%, a specificity of 95% and an overall accuracy of 93% in this study.

Conclusions

Three-dimensional MR imaging of the breast can more accurately diagnose ductal carcinomain situ. Combined with mammography, this procedure is useful for reducing the number of false-positive biopsies and helpful for deciding the better management of patients with mammographically detected suspicious microcalcifications.

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Abbreviations

DCIS:

Ductal carcinomain situ

MIP:

Maximum intensity projection

MPR:

Multiplanar reconstruction

MLO:

Mediolateral oblique

CC:

Craniocaudal

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Author information

Authors and Affiliations

  1. Breastopia Namba Hospital, Breastopia Medical Corporation, Japan

    Hiroshi Nakahara, Kiyoshi Namba, Atsuo Fukami, Ryoji Watanabe, Yorio Maeda, Hidemi Furusawa & Takafumi Matsu

  2. Department of Breast Pathology, Cancer Institute Hospital, Japan

    Futoshi Akiyama

  3. Department of Radiology, Miyazaki Medical College, Japan

    Hirotoshi Nakagawa, Hiromi Ifuku, Mayumi Nakahara & Shozo Tamura

Authors
  1. Hiroshi Nakahara
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  2. Kiyoshi Namba
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  3. Atsuo Fukami
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  4. Ryoji Watanabe
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  5. Yorio Maeda
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  6. Hidemi Furusawa
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  7. Takafumi Matsu
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  8. Futoshi Akiyama
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  9. Hirotoshi Nakagawa
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  11. Mayumi Nakahara
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  12. Shozo Tamura
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Cite this article

Nakahara, H., Namba, K., Fukami, A. et al. Three-dimensional mr imaging of mammographically detected suspicious microcalcifications. Breast Cancer 8, 116–124 (2001). https://doi.org/10.1007/BF02967490

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  • DOI: https://doi.org/10.1007/BF02967490

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