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Evaluation histochimique de ľantigène carcino-embryonnaire dans les adénomes colorectaux reséqués par polypectomie endoscopique. Résultats préliminaires

Immunohistochemical evaluation of carcinoembryonic antigen in colorectal adenomas removed during endoscopic therapeutic polypectomy preliminary results

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Acta Endoscopica

Résumé

Le but de ce travail est ďévaluer la relation entre ďune part la présence de ľantigène CEA au niveau ďadénomes côliques classés selon différents types histologiques et degrés de dysplasie et ďautre part, la transformation maligne des mêmes lésions.

D’après ľexpérience des auteurs, ľaccroissement du taux de CEA au niveau du tissu adénomateux semble un indicateur valable des modifications néoplasiques de la muqueuse côlique et constitue un argument en faveur de la sequence adénomecarcinome.

Summury

The purpose of this paper is to evaluate the relationship between presence of CEA in adenomas of large bowel, with different histotype and dysplasia grading, and risk of possible malignant transformation of these lesions.

According to our finding we believe that the demonstration of CEA increase in adenomatous tissue can be a reliable indicator of malignant change in colonic mucosa and a support for the concept of adenoma-carcinoma sequence.

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  1. Universita degli Studi di Napoli, 1º Policlinico, Napoli, Italia

    A. Di Simone & P. Esposito

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  1. A. Di Simone
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  2. P. Esposito
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Di Simone, A., Esposito, P. Evaluation histochimique de ľantigène carcino-embryonnaire dans les adénomes colorectaux reséqués par polypectomie endoscopique. Résultats préliminaires. Acta Endosc 17, 25–30 (1987). https://doi.org/10.1007/BF02965230

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  • DOI: https://doi.org/10.1007/BF02965230

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