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Cytogenetics of recurrent spontaneous aborters

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Summary

Cytogenetic studies were performed on both partners of 84 couples with a history of two or more spontaneous abortions. A gross chromosomal abnormality was identified in five of these couples. Four balanced translocation carriers were detected (46,XY,t(6:14), 46,XX,t(10:17), 46,XX,t(2:7) and 45XX,t (14:21) plus one female with sex chromosome mosaicism 46,XX/47,XXX.

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Authors and Affiliations

  1. Rotunda Hospital; The Children’s Hospital, Temple Street, and the Mater Misericordiae Hospital, Dublin

    S. P. McManus & M. A. de Arce

Authors
  1. S. P. McManus
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  2. M. A. de Arce
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The authors would like to thank the staff of the division of Genetics, Pathology Department, University College, Dublin for the work they put into the cytogenetic analysis of these patients.

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McManus, S.P., de Arce, M.A. Cytogenetics of recurrent spontaneous aborters. I.J.M.S. 155, 216–220 (1986). https://doi.org/10.1007/BF02962970

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  • DOI: https://doi.org/10.1007/BF02962970

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