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Carcinome épidermoïde œsophagien superficiel: importance d’une approche multidisciplinaire

Early oesophageal squamous cell carcinoma: importance of a multidisciplinary approach

  • Published:
Acta Endoscopica

Résumé

Le carcinome épidermoïde œsophagien représente environ 50 % des cancers œsophagiens. Le pronostic des cancers œsophagiens reste sombre; néanmoins, lorsqu’il est détecté à un stade précoce, le patient peut bénéficier d’un traitement endoscopique par mucosectomie. Une bonne collaboration entre l’endoscopiste et l’anatomopathologiste ainsi qu’une stadification pathologique correcte sur pièce de mucosectomie sont dès lors primordiales pour un suivi correct du patient et si nécessaire, un traitement complémentaire. Dans cette brève revue, nous résumons les données indispensables que doivent connaître les différents intervenants (endoscopiste et anatomopathologiste) afin de fournir le traitement le plus adéquat aux patients porteurs d’un carcinome épidermoïde œsophagien superficiel.

Summary

Squamous cell carcinoma accounts for about 50 % of œsophageal cancers. The prognosis of œsophageal cell cancer remains poor, but if detected at an early stage, patients can be treated by endoscopic mucosectomy. Good communication between endoscopist and pathologist as well as correct pathological staging on the mucosectomy specimen are of utmost importance for correct follow-up and, if needed, further treatment of the patient. In this short review we summarize what endoscopists and pathologists should know in order to provide adequate help to patients with an early œsophageal squamous cell carcinoma.

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Références

  1. Younes M, Henson DE, Ertan A, Miller CC. Incidence and survival trends of esophageal carcinoma in the United States: racial and gender differences by histological type. Scand J Gastroenterol 2002;37:1359–65.

    Article  PubMed  CAS  Google Scholar 

  2. Messmann H. Squamous cell cancer of the esophagus. Best Pract Res Clin Gastroenterol 2001;15:249–65.

    Article  PubMed  CAS  Google Scholar 

  3. Allen JW, Richardson JD, Edwards MJ. Squamous cell carcinoma of the esophagus: a review and update. Surgical Oncology 1997;6:193–200.

    Article  PubMed  CAS  Google Scholar 

  4. Koshy M, Esiashvilli N, Landry JC, Thomas CR, Jr Matthews RH. Multiple management modalities in esophageal cancer: epidemiology, presentation and progression, work-up, and surgical approaches. The Oncologist 2004;9:137–46.

    Article  PubMed  Google Scholar 

  5. Fenoglio-Preiser CM, Noffsinger GN, Lantz PE, Listrom MB, Rilke FO. Gastrointestinal Pathology an atlas and text. 2nd Ed. Lippincott Williams & Wilkins 1998.

  6. Stoner GD, Gupta A. Etiology and chemoprevention of esophageal squamous cell carcinoma. Carcinogenesis 2001;22:1737–46.

    Article  PubMed  CAS  Google Scholar 

  7. Sobin LH, Wittekind C, editors. UICC TNM Classification of malignant tumours. 6th Ed. New York, Wiley-Liss 2002.

    Google Scholar 

  8. Lewin KJ, Appelman HD. Atlas of tumor pathology. Tumors of the esophagus and stomach. New York, AFIP 1996.

    Google Scholar 

  9. Sternberg SS. Histology for Pathologists. 2nd Ed. New York, Lippincott-Raven 1997.

    Google Scholar 

  10. Hamilton SR, Aaltonen LA. Pathology & genetics: tumours of the digestive system. Lyon, IARCPress 2000.

    Google Scholar 

  11. Wang G-Q, Abnet CC, Shen Q, Lewin KJ, Sun X-D, Roth MJ, Qiao Y-L, Mark SD, Dong Z-W, Taylor PR, Dawsey SM. Histological precursors of œsophageal squamous cell carcinoma: results from a 13-year prospective follow up study in a high risk population. Gut 2005;54:187–92.

    Article  PubMed  Google Scholar 

  12. Yuasa N, Miyachi M, Yasui A, Hayakawa N, Hattori T, Yoneyama F, Hirabayashi N, Nimura Y. Clinicopathological features of superficial spreading and nonspreading squamous cell carcinoma of the esophagus. Am J Gastroenterol 2001;96:315–21.

    Article  PubMed  CAS  Google Scholar 

  13. Arista-Nasr J, Rivera I, Martinez-Benitez B, Bornstein-Quevedo L, Orozco H, Lugo-Guevara Y. Atypical regenerative hyperplasia of the esophagus in endoscopic biopsy. A mimicker of squamous esophagic carcinoma. Arch Pathol Lab Med 2005;129:899–904.

    PubMed  Google Scholar 

  14. Lambert R, Lightdale CJ. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon. Gastrointestinal endoscopy 2003;58:s1-s26.

    Article  Google Scholar 

  15. Tajima Y, Nakanishi Y, Tachimori Y, Kato H, Watanabe H, Yamaguchi H, Yoshimura K, Kusano M, Shimoda T. Significance of involvement by squamous cell carcinoma of the ducts of esophageal submucosal glands. Cancer 2000;83:248–54.

    Article  Google Scholar 

  16. Endo M, Yoshino K, Kawano T, Nagai K, Inoue H. Clinicopathologic analysis of lymph node metastasis in surgically resected superficial cancer of the thoracic esophagus. Dis Esoph 2000;13:125–29.

    Article  CAS  Google Scholar 

  17. Eguchi T, Nakanishi Y, Shimoda T, Iwasaki M, Igaki H, Tachimori H, Kato H, Yamaguschi H, Saito D, Umemura S. Histopathological criteria for additional treatment after endoscopic mucosal resection for esophageal cancer: analysis of 164 surgically resected cases. Modern Pathology 2006;19:475–80.

    Article  PubMed  Google Scholar 

  18. Higuchi K, Tanabe S, Sasaki T, Nakatani K, Saigenji K, Kobayashi N, Mitomi H. Expansion of the indications for endoscopic mucosal resection in patients with superficial esophageal carcinoma. Endoscopy 2007;39:36–40.

    Article  PubMed  CAS  Google Scholar 

  19. Schlemper RJ, Riddell RH, Kato Y, Borchard F, Cooper HS, Dawsey SM, Dixon MF, Fenoglio-Preiser CM, Fléjou JF, Geboes K, Hattori T, Hirota T, Itabashi M, Iwafuchi M, Iwashita A, Kim YI, Kirchner T, Klimpfinger M, Koike M, Lauwers GY, Lewin KJ, Oberhuber G, Offner F, Price AB, Rubio CA, Shimizu M, Shimoda T, Sipponen P, Solcia E, Stolte M, Watanabe H, Yamabe H. The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000;47:251–5.

    Article  PubMed  CAS  Google Scholar 

  20. Tanière P, Peysson P, Scoazec J-Y. Prise en charge des pièces de mucosectomie endoscopique digestive. Ann Pathol 2001;21:285–88.

    PubMed  Google Scholar 

  21. Lauwers GY, Ban S, Mino M, Ota S, Matsumoto T, Arai S, Chan H-H, Brugge WR, Shimizu M. Endoscopic mucosal resection for gastric epithelial neoplasms: a study of 39 cases with emphasis on the evaluation of specimens and recommendations for optimal pathologic analysis. Modern Path 2004;17:2–8.

    Article  Google Scholar 

  22. Pech O, May A, Gossner L, Rabenstein T, Manner H, Huijsmans J, Vieth M, Stolte M, Berres M, Ell C. Curative endoscopic therapy in patients with early esophageal squamous-cell carcinoma or high-grade intraepithelial neoplasia. Endoscopy 2007;39:30–35.

    Article  PubMed  CAS  Google Scholar 

  23. Eski M, Matsumoto T, Hirakawa K, Nakamura S, Umeno J, Koga H, Yao T, Lida M. Risk factors for local recurrence for superficial esophageal cancer after treatment by endoscopic mucosal resection. Endoscopy 2007;39:41–45.

    Article  Google Scholar 

  24. Ciocirlan M, Lapalus MG, Hervieu V, Souquet JC, Napoléon B, Scoazec J-Y, Lefort C, Saurin JC, Ponchon T. Endoscopic mucosal resection for squamous premalignant and early malignant lesions of the esophagus. Endoscopy 2007;39:24–29.

    Article  PubMed  CAS  Google Scholar 

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Nagy, N., Demetter, P. Carcinome épidermoïde œsophagien superficiel: importance d’une approche multidisciplinaire. Acta Endosc 38, 107–115 (2008). https://doi.org/10.1007/BF02961948

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  • DOI: https://doi.org/10.1007/BF02961948

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