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Henry Thomson Lynch, un itinéraire exemplaire de la génétique clinique à la biologie moléculaire

Henry Thomson Lynch, an exemplary path from clinical to molecular genetics

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Acta Endoscopica

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Abbreviations

CCR :

Cancer ColoRectal

CIMP + :

Cpg-Island Methylator Phenotype +

CpG :

Cytosine-phosphate-Guanine

EXO1 :

EXOnuclease 1

HNPCC :

Hereditary NonPolyposis Colorectal Cancer

ICG-HNPCC :

International Collaborative Group on Hereditary NonPolyposis Colorectal Cancer

IHC :

ImmunoHistoChimie

InSiGHT :

International Society for Gastrointestinal Hereditary Tumors

MLH1 (ou hMLH1) :

MutL,E. coli, human Homolog 1

MMR :

MisMatch Repair »i.e. réparation des mésappariements de l’ADN

MSH2 (ou hMSH2) :

MutS,E. coli, human Homolog 2

MSH6 (ou hMSH6) :

MutS,E. coli, human Homolog 6

MSI :

MicroSatellite Instability

MSI-H :

MSI «High»

MSI-L (ou MSI -) :

MSI «Low»

MSS :

MicroSatellite Stable

MYH :

Mut Y human Homolog

PAF :

Polypose Adénomateuse Familiale

PMS1 :

PostMeiotic Segregation increased,S. cerevisiae, 1

PMS2 :

PostMeiotic Segregation increased,S. cerevisiae, 2

RER :

Replication ERrors

TGFß-R2 :

Transforming Growth Factor ß-Receptor 2

CRC :

ColoRectal Cancer

CIMP + :

Cpg-Island Methylator Phenotype +

CpG :

Cytosine-phosphate-Guanine

EXO1 :

EXOnuclease 1

HNPCC :

Hereditary NonPolyposis Colorectal Cancer

ICG-HNPCC :

International Collaborative Group on Hereditary NonPolyposis Colorectal Cancer

IHC :

ImmunoHistoChemistry

InSiGHT :

International Society for Gastrointestinal Hereditary Tumors

MLH1 (o hMLH1) :

MutL,E. coli, human Homolog1

MMR :

MisMatch

MSH2 (or hMSH2) :

MutS,E. coli, human Homolog 2

MSH6 (or hMSH6) :

MutS,E. coli, human Homolog 6

MSI :

MicroSatellite Instability

MSI-H (or MSI +) :

MSI High

MSI-L (or MSI -) :

MSI Low

MSS :

MicroSatellite Stable

MYH :

Mut Y human Homolog

FAP :

Familial Adenomatous Polyposis

PMS1 :

PostMeiotic Segregation increased,S. cerevisiae, 1

PMS2 :

PostMeiotic Segregation increased,S. cerevisiae, 2

RER :

Replication ERrors

TGFß-R2 :

Transforming Growth Factor ß-Receptor 2

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  1. Emerite à l’Université Paris 7, France

    C. Matuchansky (Professeur)

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  1. C. Matuchansky
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Correspondence to C. Matuchansky.

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Matuchansky, C. Henry Thomson Lynch, un itinéraire exemplaire de la génétique clinique à la biologie moléculaire. Acta Endosc 37, 491–508 (2007). https://doi.org/10.1007/BF02961797

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  • DOI: https://doi.org/10.1007/BF02961797

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