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Chemotherapy treated hodgkins disease — A fifteen year review

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Summary

A Review of ninety seven patients with Hodgkin’s disease treated with chemotherapy at a single institution is reported. Fifty were male and forty seven female. The mean age at diagnosis was 32.9 years (range : 11–79 years).

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References

  • Bergsagel, D. E., Alison, R. E., Bean, H. A., Brown, T. C., Bush, R. S., Clarke, R. M.et al. 7 others). 1982. Results of treating Hodgkin’s disease without a policy of laparotomy staging. Cancer Treat. Rep. 66, 717–731.

    PubMed  CAS  Google Scholar 

  • Bonadonna, G., Viviani, S., Bonfante, V., Valgussa, P., Santoro, A. 1984. Alternating chemotherapy with MOPP/ABVD in Hodgkin’s disease: update results. Proceedings of the American Society of Clinical Oncology. 3, 254.

    Google Scholar 

  • Carter, S. K. and Livingstone, R. B. 1973. Single-agent therapy for Hodgkin’s disease. Arch. Intern. Med. 131, 377–387.

    Article  PubMed  CAS  Google Scholar 

  • Coltman, C. A. and Dixon, D. O. 1982. Second malignancies complicating Hodgkin’s disease: A South-West oncology group ten year follow up. Cancer Treat. Rep. 66, 1023.

    PubMed  Google Scholar 

  • Cunningham, J., Mauch, P., Rosenthal, D. S., Canellos, G. P. 1982. Longterm complications of MOPP chemotherapy in patients with Hodgkin’s disease. Cancer Treat. Rep. 66, 1015–1022.

    PubMed  CAS  Google Scholar 

  • De Vita, V. T. (Jr.), Serpick, A., Carbone, P. P. 1970. Combination chemotherapy in the treatment of advanced Hodgkin’s disease. Ann. Intern. Med. 73, 881.

    Google Scholar 

  • Goldsmith, M. A. and Carter, S. K. 1974. Combination chemotherapy of advanced Hodgkin’s disease—a review. Cancer 33, 1–7.

    Article  PubMed  CAS  Google Scholar 

  • Haybittle, J. L., Easterling, M. J., Bennett, M. H.et al. 1985. Review of British National Lymphoma Investigation Studies of Hodgkin’s disease and development of prognostic index. Lancet i, 967–972.

    Article  Google Scholar 

  • Hoppe, R. T., Portlock, C. S., Glatstein, E., Rosenberg, S. A., Kaplan, H. S. 1979. Alternating chemotherapy and irradiation in the treatment of advanced Hodgkin’s disease. Cancer 43, 472.

    Article  PubMed  CAS  Google Scholar 

  • Kaye, S. B., Juttner, C. A., Smith, I. E., Barrett, A., Austin, D. F., Peckham, M. J., McElwain, T. J. 1979. Three years experience with ChlVPP (A combination of drugs with low toxicity) for the treatment of Hodgkin’s disease. Br. J. Cancer 39, 168–174.

    PubMed  CAS  Google Scholar 

  • Larson, R. A. and Ulmann, J. E. 1982. The strategic role of laparotomy in staging Hodgkin’s disease. Cancer Treat. Rep. 66, 727–734.

    Google Scholar 

  • Lee, D., Anderson, J. R., Stirling, M. L., French, M., Naysmith, A. 1981. The value of staging laparotomy in Hodgkin’s disease—three years experience of the Edinburgh Lymphoma Group. Clin. Oncol. 7, 105–114.

    PubMed  CAS  Google Scholar 

  • Lister, T. A. 1985. Hodgkin’s disease in adults: The challenge. Postgrad. Med. J. 61, 103–107.

    PubMed  CAS  Google Scholar 

  • Lukes, R. J. and Butler, J. J. 1966. The pathology and nomenclature of Hodgkin’s disease. Cancer Res. 36, 1310.

    Google Scholar 

  • McElwain, T. J. 1983. Solid tumours of the lymphoid system. Medicine International. 1 (26), 1218–1224.

    Google Scholar 

  • McVie, J. G. and Somers, R. 1985. Chemotherapy of Hodgkin’s disease comes of age. Br. Med. J. 290, 950–951.

    CAS  Google Scholar 

  • Moore, M. R., Bull, J. M., Jones, S. E., Rosenberg, S. A., Kaplan, H. S. 1972. Sequential radiotherapy and chemotherapy in the treatment of Hodgkin’s disease; a progress report. Ann. Intern. Med. 77, 1.

    PubMed  CAS  Google Scholar 

  • Nixon, D. W. and Aisenberg, A. C. 1974. Combination chemotherapy of Hodgkin’s disease. Cancer 33, 1499–1504.

    Article  Google Scholar 

  • Peto, R., Pike, M. C., Armitage, P., and seven others. 1976/1977. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Br. J. Cancer 34, 583–612 and 35, 1-39.

    Google Scholar 

  • Powderly, W. G., Cantwell, B. M., Fennelly, J. J., Warde, P., McCabe, M. M., Towers, R. P. 1985. Renal glomerulopathies associated with Hodgkin’s disease. Cancer 56(4), 874–875.

    Article  PubMed  CAS  Google Scholar 

  • Prosnitz, L. R., Farber, L. R., Fischer, J. J., Bertino, J. R., Fisher, D. B. 1976. Long-term remissions with combined modality therapy for advanced Hodgkin’s disease. Cancer 37, 2826.

    Article  PubMed  CAS  Google Scholar 

  • Rosenberg, S. A., Kaplan, H. S., Glatstein, E. J., Portlock, C. S. 1978. Combined modality therapy in Hodgkin’s disease. A report on the Stanford trials. Cancer 42, 991.

    Article  PubMed  CAS  Google Scholar 

  • Santoro, A. and Bonadonna, G. 1979. Prolonged disease-free survival in MOPP-resistant Hodgkin’s disease after treatment with Adriamycin, Bleomycin, Vinblastine and Decarbazine [ABVD]. Cancer Chemother. Pharmacol. 2, 101–105.

    Article  PubMed  CAS  Google Scholar 

  • Suthcliffe, S. B., Wrigley, P. F. M., Peto, J. (and five others). 1978. MVPP chemotherapy regimen for advanced Hodgkin’s disease. Br. Med. J. 1, 679.

    Google Scholar 

  • Symposium on Staging in Hodgkin’s disease. Ann. Arbor, Mich. 1971. Cancer Res. 1, 31.

  • Tubiana, M., Henry-Amar, M., Hayat, M.et al. 1985. Prognostic factors in Hodgkin’s disease. Lancet ii, 165.

    Article  Google Scholar 

  • Van Dongen, J. A., Somers, R., Burgers, J. M. V., Hart, A. A. M. 1979. Staging laparotomies in Hodgkin’s disease and non-Hodgkin’s Lymphoma: Changing ideas on indications. Clin. Oncol. 5, 201–208.

    PubMed  Google Scholar 

  • Waxman, J. H., Terry, Y. A., Wrigley, P. F. M., Malpas, J. S., Rees, L. H., Besser, G. M., Lister, T. A. 1982. Gonadal function in Hodgkins disease; long-term follow-up of chemotherapy. Br. Med. J. 285, 1612.

    CAS  Google Scholar 

  • Waxman, J. 1985. Cancer, chemotherapy and fertility. Br. Med. J. 290, 1096–1097.

    Article  CAS  Google Scholar 

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The authors sincerely acknowledge the help of Dr. B. Hourihane, Dr. M. Moriarty and Dr. S. Cahalane in the management of the patients included in this study. We are also grateful to Dr. B. Cantwell for his invaluable advice and support.

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Bourke, J.P., Fennelly, J.J., Duggan, J. et al. Chemotherapy treated hodgkins disease — A fifteen year review. I.J.M.S. 155, 300–307 (1986). https://doi.org/10.1007/BF02960708

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