Abstract
Objective: To study the therapeutic effect of Chinese herbal medicine (CHM) for supplementing Qi, activating blood circulation and tonifying Kidney on prevention and treatment of diabetes in middle and aged women with Kidney Deficiency and bone metabolic disturbance.Methods: Clinical observation was taken in 52 patients, who were divided into two groups, the control group (treated with hypoglycemic agent alone) and the treated group (treated with hypoglycemic agent and CHM).Results: Before treatment, patients in both groups showed obviously higher blood alkaline phosphatase, β2-microglobulin (β2-MG) level, urinary β2-MG, calcium and phosphorus level, but lower serum estradiol level than those in normal subjects. After 3 months’ treatment, no apparent change in serum estradiol level was observed, but other parameters were all lowered obviously in the two groups, with the changes revealed more obviously in the treated group. The symptoms of Kidney Deficiency, such as lumbodorsal pain, fatigue, palpitation and vertigo, were improved after treatment, which was also more obviously in the treated group.Conclusion: CHM for supplementing Qi, activating blood circulation and tonifying Kidney was effective in improving Kidney Deficiency and mineral substance loss in bones in middle and aged diabetic women patients. The CHM and western drugs acted synergistically.
Similar content being viewed by others
References
Cai XJ, Zhang Y, Huang SL. Preliminary exploration on the changes of bone mineral contents of Kidney deficient patients. CJIM 1994; 14(3): 154–155.
Liu DG, YE EM, Hou ZK, et al. Exploration on replenishing Kidney and regulating ovarian function—analysis of 56 cases. CJIM 1984;4(8): 476–477.
Wei JA, Chen XH, LI CJ, et al. The effect of Shenxu Gutong capsule on the bone density of menopausal women. J of TCM 1995;36(9):548–550.
Zhang XQ, Guo SS. Survey of clinical application of tonifying Kidney and activating blood circulation. CJIM 1994;14(6):376–378.
Kuang AK. Chief Editor. Handbook of internal medicine. 3rd Edition. Shanghai: Shanghai Press of Science and Technology, 1990: 667–669.
Shi JR, Jia SY. Handbook of clinical examination. Jinan: Shandong Press of Science and Technology, 1988: 764–765, 773–776.
Zhu LQ, Liu YH, Wang WZ. Observation on HbA1c, TXB2, 6-Keto-PGF1 α of diabetic patients before and after integrated treatment. New TCM and Pharmacology 1998; 30(3):40–42.
Shen L, DU JY, Yang BY, et al. Clinical study on the bone material lose of post menopausal women with tonifying Kidney principle. CJIM 1994;14(9):515–518.
LI QN, WU T, Xie H, et al. The effect of Epimedium extract on the bone metabolism of castrated rats. Chin Herb Med 1993; 24(12): 637- 638, 658.
Lin YY, Chen YS, Han XM, et al. The effect of warming Yang herbs on the uteroestrogen receptor of hypothalamas-pitutiary-adrenal cortex axis inhibited rats model. CJIM 1985;5(3): 175–177.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Zhu, L., LI, H. & Liu, Y. Study on prevention and treatment of diabetes in middle and aged women with kidney deficiency and bone metabolic disturbance. CJIM 6, 192–195 (2000). https://doi.org/10.1007/BF02950924
Issue Date:
DOI: https://doi.org/10.1007/BF02950924