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Comparative clinical study of duodongning and ritalin in treating attention- deficit/hyperactivity disorder) and ritalin in treating attention- deficit/hyperactivity disorder

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Abstract

Objective: To study the effect and side-effects of Duodongning (DDN), a traditional Chinese medicine (TCM) granule in treating attention-deficit/hyperactivity disorder (ADHD).Methods: Double blind method was used to compare DDN with ritalin for ADHD in clinical practice from December 1995 to December 1996. The total number of cases was 70.Results: There were 37 cases in DDN group, with 17 cases (45.9 %) markedly effective, 16 cases (43.2%) effective, the Conners hyperactive index (HI) 2. 01 ± 0. 83 (before treatment), 1.17 ± 0.76 (after 4 weeks ’ treatment); and there were 33 cases in the ritalin group, with 15 cases (45.5%) markedly effective, 14 cases (42.4%) effective, HI2.07±0.91 (before treatment), 1.47±0.79 (after 4 weeks’ treatment). Insignificant difference existed between the effectiveness in these 2 groups (P > 0.05). The chief side-effects were 3 cases (8.1%) of anorexia in DDN group, and 7 cases (21.2%) in ritalin group.Conclusion: The effect of DDN is not significantly different from that of ritalin, and the side-effects in ritalin group were more than those in DDN group.

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Authors and Affiliations

  1. Institute of Mental Health of the Second Affiliated Hospital, Hunan Medical University, 410011, Changsha

    Xuerong Li

  2. Pharmaceutic Factory of Hunan, China

    Zhijian Chen

Authors
  1. Xuerong Li
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  2. Zhijian Chen
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Li, X., Chen, Z. Comparative clinical study of duodongning and ritalin in treating attention- deficit/hyperactivity disorder) and ritalin in treating attention- deficit/hyperactivity disorder. CJIM 6, 181–183 (2000). https://doi.org/10.1007/BF02950920

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