Abstract
Objective: To observe the clinical effect of puerarin in treatment of infantile viral myocarditis.Methods: Puerarin was administered intravenously together with conventional treatment in the treated group, while conventional treatment alone was given to the control group. Creatine kinase isoenzyme, lactate dehydrogenase isoenzyme, cardiac function and clinical manifestations before and after treatment were observed.Results: Puerarin could significantly relieve the symptoms in patients of infantile viral myocarditis, enhance the metabolism of myocardium and improve the cardiac function. The total effective rate in the treated group was 87.04 %, significantly higher than that of the control group, the difference between them was significant (P < 0.05).Conclusion: Puerarin can be used to treat patients with infantile viral myocarditis with satisfactory results.
Similar content being viewed by others
References
Fan Ll, Zeng Gy, Zhou Yp, et al. Pharmacological study of pueraria lobata II. Action of pueraria flavone on coronary circulation, myocardial hemodynamics and myocardium metabolism in dogs. Chin Med J 1975;55(10): 724–727.
LI XY, Wang Pr, Shao Jh, et al. Effect of intravenously injected puerarin on size of acute myocardial infarction. J Shangdong Medical College 1984;22(3): 9–12.
LI XY, Wang Pr, Shao Jh. Effect of puerarin on the size on myocardial infarction. J Chin Cardiovascular Dis 1985; 13(3): 175–178.
Chai XS, Wang Zx, Chen Pn, et al. Effect of puerarin on antiarrhythmia. J Chin Pharmacology 1985; 16(3): 166–168.
LI JY. Explanation on revised diagnosis standard of myocarditis. J Chin Pediatrics 1994; 32:329.
Meng P, Zhou Df, Zhang Yx, et al. Using99mTc-myocardium perfusion topography in diagnosing viral myocarditis. Prac J Pediatrics Clin 1996;11(6):336.
LU XR, Gao X, XU LZ, et al. Blocking effect of puerarin on isolated organ and whole animal that contains βadrenergic receptor. J Chin Pharmacology 1986; 7(6): 537–539.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Meng, P., Zhou, D., Hu, X. et al. Clinical observation on the treatment of infantile viral myocarditis with puerarin. CJIM 6, 178–180 (2000). https://doi.org/10.1007/BF02950919
Issue Date:
DOI: https://doi.org/10.1007/BF02950919