Summary
The influence of cortisone therapy on the plasma electrophoretic patterns was studied in pregnancy toxæmia, rheumatoid arthritis, rheumatic fever and osteaorthritis mutilans. The results obtained in pregnancy toxaemia were varied and did not indicate any specific effect. The plasma electrophoretic pattern in a case of rheumatoid arthritis became more normal. Plasma from patients with osteoarthritis mutilans and rheumatic fever showed no significant changes.
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Additional information
Fifth Report of the clinical Cortisone Sub-Committee of the Medical Research Council of Ireland (Prof. Henry Moore, Chairman and Clinical Director, Prof. J. W. E. Jessop and Prof. D. K. O. Donovan).
The Medical Research Council of Ireland is indebted to Dr. James J. Kerrigan and Dr. James M. Carlisle for the gift of cortisone (Cortone-Merck) which rendered possible the treatment of the patients mentioned in this communication.
The author wishes to thank Dr. B. Quinn, Dr. M. Hickey, Dr. C. J. McSweeney and Dr. O. Fitzgerald and Dr. M. Drury for their helpful co-operation.
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McCarthy, E.F. The effect of cortisone administration on the electrophoretic pattern of the plasma proteins in certain pathological conditions. Ir J Med Sci 28, 102–107 (1953). https://doi.org/10.1007/BF02950880
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DOI: https://doi.org/10.1007/BF02950880