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Der geriatrische Patient aus chirurgischer Sicht — Perioperative Aspekte

The surgical point of view of the geriatric patient — perioperative aspects

  • Themenschwerpunkt: Der Geriatrische Patient Aus Chirurgischer Sicht — Teil 1
  • Published:
Acta Chirurgica Austriaca Aims and scope Submit manuscript

Zusammenfassung

Grundlagen: Aufgrund der raschen Zunahme des Anteils der älteren Bevölkerung an der Gesamtbevölkerung steigt auch deren medizinischer Versorgungsbedarf. Chronologisches Alter per se bedeutet heute allerdings keine Kontraindikation mehr für die Durchführung eines diagnostisch-interventionellen oder operativen Eingriffes.

Methodik: Zunächst ist es wichtig, zwischen dem chronologischen und dem wesentlich aussagekräftigeren, biologischen Alter eines Patienten zu unterscheiden. Die wenigen bis dato vorliegenden Untersuchungen zeigen, dass sämtliche Organsysteme einem Alterungsprozess unterworfen sind. Meist reicht die Funktion der Organsysteme eines alten Menschen aus, um den Anforderungen des Alltags gerecht zu werden, die funktionelle Leistungsreserve ist aber oft eingeschränkt, was in Ausnahmesituationen relevant werden kann. Im Falle einer geplanten Operation ist es dann daher wichtig, die funktionelle Leistungsreserve zu evaluieren. Darauf basierend wird ein perioperatives Behandlungskonzept erarbeitet, das durch präoperative Verbesserung der Ausgangslage (Stoffwechsel, Hämodynamik) und individueller, präziser Betreuung reversible und irreversible Defizite verhindern hilft.

Ergebnisse: Die gewaltigen apparativ-technischen und pharmakologischen Fortschritte der letzten Jahre haben allgemeinund regionalanästhesiologische Verfahren noch besser steuerbar und damit sicherer gemacht. Mittels nicht-invasiven und invasiven Verfahren können Störungen in Organsystemen schon früh entdeckt und folgerichtig therapiert werden. Um ein perfektes perioperatives Gesamtergebnis zu erzielen, ist die volle Ausnützung der Möglichkeiten der postoperativen Schmerztherapie ebenso wichtig wie die Sicherstellung einer letztlich ganzheitsmedizinischen Intensivtherapie, deren Bedarf in den nächsten Jahren sicherlich noch steigen wird.

Schlussfolgerungen: Somit ist konzeptionell immer davon auszugehen, dass der geriatrische Patient nicht einfach ein alter Mensch ist, sondern zu einer vollkommen eigenständigen Patientengruppe mit eigenen physiologischen und pharmakodynamischen Gesetzmäßigkeiten gehört.

Summary

Background: With the background of an increasing number of elderly people, their need of medical support gains more and more importance. However, chronological age per se is no longer a contraindication for performing diagnostic-interventional or surgical procedures.

Methods: With this in mind, it is of interest to differentiate between the chronological and the much more useful, biological age of a patient. The published data indicate that ageing influences each organ in its function. In most cases, the individual organs cope with the requirements of daily life. Nevertheless, there is a reduction of functional organ reserve which may become clinically significant in an exceptional situation like an operation. Therefore, in case of an elective surgical procedure, it is necessary to evaluate this functional reserve. Based on this information, a perioperative treatment plan is to be designed which helps to prevent reversible or irreversible deficits by improving both the preoperative status (e. g. hemodynamic and respiratory condition, metabolism) and the individual intraoperative treatment and postoperative care of the patient.

Results: As a result of the respective technical and pharmacological developments in the course of the last two decades, general and regional anesthesia has become more goal directed, better controllable and, therefore, more secure. Thus, by the use of both non-invasive and invasive monitoring devices disturbances within any organ can be detected to enable early and consequent therapeutic measures. In order to obtain a perfect perioperative result, the postoperative treatment plan has also to include all aspects of modern pain therapy and intensive care, if necessary. For the latter an increasing demand is to be expected over the subsequent years.

Conclusions: In summary, the geriatric population does not consist simply of older patients, but rather represents itself as an entity with its own physiologic and pharmacodynamic principles.

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Literatur

  1. New York Heart Association (NYHA) Classification; http://www.hcoa.org/hcoacme/chf-cme/chf0070.htm.

  2. Barash PG, Cullen BF, Stoelting RK: Clinical Anesthesia. 3rd ed. Lippincott-Raven Publishers, 1977.

  3. Brooker CD, Sutherland J, Cousins MJ: Propofol maintenance to reduce post-operative emesis in thyroidectomy patients: a group sequential comparison with isoflurane/nitrous oxide. Anaesth Intensive Care 1998;26:625–629.

    PubMed  CAS  Google Scholar 

  4. Butcher S, Chahel H, Lord JM: Review article: ageing and the neutrophil: no appetite for killing? Immunology 2000;100:411–416.

    Article  PubMed  CAS  Google Scholar 

  5. Cockcroft DW, Gault MH: Prediction of creatinine clearence of serum creatinine. Nephron 1976;16:31–41.

    Article  PubMed  CAS  Google Scholar 

  6. Davis FM, Woolner DF, Frampton C, Grant A, Harrison RT, Roberts MT, Thadaka R: Prospective, multi-centre trial of mortality following general or spinal anaesthesia for hip fracture surgery in the elderly. Br J Anaesth 1987;59:1080–1088.

    Article  PubMed  CAS  Google Scholar 

  7. Ettorre GM, Sommacale D, Farges O, Sauvanet A, Guevara O, Belghiti J: Postoperative liver function after elective right hepatectomy in elderly patients. Br J Surg 2001;88:73–76.

    Article  PubMed  CAS  Google Scholar 

  8. Folkow B, Svanborg A: Physiology of cardiovascular ageing. Physiol Rev 1993;73:725–764.

    PubMed  CAS  Google Scholar 

  9. Fu A, Nair KS: Age effect on fibrinogen and albumin synthesis in humans. Am J Physiol 1998;275:1023–1030.

    Google Scholar 

  10. Fulop JT, Worum I, Csongor J, Foris G, Leovey A: Body composition in elderly people. I. Determination of body composition by multiisotope method and the elimination kinetics of these isotopes in healthy elderly subjects. Gerontology 1985;31:6–14.

    Article  PubMed  Google Scholar 

  11. Goldman L, Caldera DL, Nussbaum SR, Southwick FS, Krogstad D, Murray B, Burke DS, O’Malley TA, Goroll AH, Caplan CH, Nolan J, Carabello B, Slater EE: Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med 1977;297:845–850.

    PubMed  CAS  Google Scholar 

  12. Han SN, Meydani SN: Antioxidants, cytokines, and influenza infection in aged mice and elderly humans. J Infect Dis 2000;182(Suppl 1):74–80.

    Article  Google Scholar 

  13. Helderman JH, Vestal RE, Rowe JW, Tobin JD, Andres R, Robertson GL: The response of arginine vasopressin to intravenous ethanol and hypertonic saline in man: The impact of ageing. J Gerontol 1978;33:39–47.

    PubMed  CAS  Google Scholar 

  14. Kampmann JP, Sinding J, Moller-Jorgensen I: Effect of age on liver function. Geriatrics 1975;30:91–95.

    PubMed  CAS  Google Scholar 

  15. Katlic MR: Surgery in centenarians. JAMA 1985;253:3139–3141.

    Article  PubMed  CAS  Google Scholar 

  16. Katoh T, Bito H, Sato S: Influence of age on hypnotic requirement, bispectral index, and 95 % spectral edge frequency associated with sedation induced by sevoflurane. Anesthesiology 2000;92:55–61.

    Article  PubMed  CAS  Google Scholar 

  17. Kirsch M, Guesnier L, LeBesnerais P, Hillion ML, Debauchez M, Seguin J, Loisance DY: Cardiac operations in octogenarians: Perioperative risk factors for death and impaired autonomy. Ann Thorac Surg 1998;66:60–67.

    Article  PubMed  CAS  Google Scholar 

  18. Kurz A, Plattner O, Sessler DI, Huemer G, Redl G, Lackner F: The threshold for thermoregulatory vasoconstriction during nitrous oxide/isoflurane anesthesia is lower in elderly than in younger patients. Anesthesiology 1993;79:465–469.

    Article  PubMed  CAS  Google Scholar 

  19. Lindeman RD: Renal physiology and apathophysiology of ageing. Contrib Nephrol 1993;105:1–12.

    PubMed  CAS  Google Scholar 

  20. Marhofer P, Schrögendorfer K, Koinig H, Kapral S, Weinstabl C, Mayer N: Ultrasonographic guidance improves sensory block and onset of three-in-one blocks. Anesth Analg 1997;85:854–857.

    Article  PubMed  CAS  Google Scholar 

  21. Marx GF, Mateo CV, Orkin LR: Computer analysis of postanesthetic deaths. Anesthesiology 1973;39:54–58.

    Article  PubMed  CAS  Google Scholar 

  22. Melamed E, Lavy S, Bentin S, Cooper G, Rinot Y: Reduction in regional cerebral blood flow during normal ageing in men. Stroke 1980;11:31–35.

    PubMed  CAS  Google Scholar 

  23. Moller JT, Cluitsmans P, Rasmussen LS, Houx P, Rasmussen H, Canet J, Rabbitt P, Jolles J, Larsen K, Hanning CD, Langeron O, Johnson T, Lauvern PM, Kristensen PA, Biedler A, vanBeem H, Fraidakis O, Silverstein JH, Beneken JE, Gravenstein JS: Long-term postoperative cognitive dysfunction in elderly ISPOCD1 study. Lancet 1998;351:857–861.

    Article  PubMed  CAS  Google Scholar 

  24. Naritomi H, Meyer JS, Sakai F, Yamaguchi F, Shaw T: Effect of advancing age on regional cerebral blood flow. Studies in normal subjects and aubjects with risk factors for atherothrombotic stroke. Arch Neurol 1979;36:410–416.

    PubMed  CAS  Google Scholar 

  25. Ochsner A: Is risk of operation too great in the elderly? Geriatrics 1967;22:121–130.

    PubMed  CAS  Google Scholar 

  26. Republik Österreich, Ö.S.Z. (ed): Statistisches Jahrbuch für die Republik Österreich 1999. Wien, Österreichische Staatsdruckerei, 1999.

  27. Rodeheffer RJ, Gerstenblith G, Becker LC, Fleg JL, Weisfeldt ML, Lakatta EG: Exercise cardiac output is maintained with advancing age in healthy human subjects: Cardiac dilatation and increased stroke volume compensate for a diminished heart rate. Circulation 1984;69:203–213.

    PubMed  CAS  Google Scholar 

  28. Schmucker DL: Ageing and the liver: an update. J Gerontol A Biol Sci Med Sci 1998;53:315–320.

    Google Scholar 

  29. Shore-Lesserson L, Manspeizer HE, DePerio M, Francis S, Vela-Cantos F, Ergin MA: Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery. Anesth Analg 1999;88:312–319.

    Article  PubMed  CAS  Google Scholar 

  30. Smith OC: Advanced age as a contraindication to operation. Med Rec (NY) 1907;72:642.

    Google Scholar 

  31. Sohn TA, Yeo CJ, Cameron JL, Lillemoe KD, Talamini MA, Hruban RH, Sauter PK, Coleman J, Ord SE, Grochow LB, Abrams RA, Pitts HA: Should pancreaticoduodenectomy be performed in octogenarians? J Gastrointest Surg 1998;2:207–216.

    Article  PubMed  CAS  Google Scholar 

  32. Suttner SW, Schmidt CC, Boldt J, Huttner I, Kumle B, Piper SN: Low-flow desflurane and sevoflurane anesthesia minimally affect hepatic integrity and function in elderly patients. Anesth Analg 2000;91:206–212.

    Article  PubMed  CAS  Google Scholar 

  33. Tolep K, Kelsen SG: Effect of ageing on respiratory skeletal muscles. Clin Chest Med 1993;14:363–378.

    PubMed  CAS  Google Scholar 

  34. Valentin N, Lomholt B, Jensen JS, Hejgaard N, Kreiner S: Spinal or general anaesthesia for surgery of the fractured hip? A prospective study of mortality in 578 patients. Br J Anaesth 1986;58:284–291.

    Article  PubMed  CAS  Google Scholar 

  35. Wahba WM: Influence of ageing on lung function: Clinical significance of changes from age twenty. Anesth Analg 1983;62:764–776.

    Article  PubMed  CAS  Google Scholar 

  36. Warden JC, Borton CL, Horan BF: Mortality associated with anesthesia in New South Wales, 1984–1990. Med J Aust 1994;161:585–593.

    PubMed  CAS  Google Scholar 

  37. Zoli M, Magalotti D, Bianchi G, Gueli C, Orlandini C, Grimaldi M, Marchesini G: Total and functional hepatic blood flow decrease in parallel with ageing. Age Ageing 1999;28:29–33.

    Article  PubMed  CAS  Google Scholar 

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Gonano, C., Kettner, S.C., Seibt, F.A. et al. Der geriatrische Patient aus chirurgischer Sicht — Perioperative Aspekte. Acta Chir. Austriaca 33, 218–222 (2001). https://doi.org/10.1007/BF02950328

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  • DOI: https://doi.org/10.1007/BF02950328

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