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Subacute sclerosing panencephalitis: Report of two cases

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Summary

Two cases of subacute sclerosing panencephalitis are described. Both were shown to be associated with measles-virus infection. Some aspects of this rare condition are described.

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References

  • Adams, J. M. 1968. Clinical pathology of measles encephalitis and sequalae. Neurology (Minneap.) 18, Part 2, 2.

    Google Scholar 

  • Bouteille, M., Fontaine, C., Vedrenne, C. and Delarne, J. 1965. Sur un case d’encephalite subaigue a inclusions. Etude anatomoclinique et ultra structurale. Rev. Neurol. 118, 454.

    Google Scholar 

  • Brody, J. A. and Detels, R. 1970. Subacute sclerosing panencephalitis: A zoonosis following aberrent measles. Lancet ii, 500.

    Article  Google Scholar 

  • Brody, J. A., Detels, R. and Sever, J. L. 1972. Measles antibody titres in sibships of patients with subacute sclerosis panencephalitis and controls. Lancet i, 177.

    Article  Google Scholar 

  • Burnet, F. M. 1968. Measles as an index of immunological function. Lancet ii, 610.

    Article  Google Scholar 

  • Connolly, J. H., Allen, Ingrid, Hurwitz, L. J. and Millar, J. H. D. 1967. Measles-virus antibody and antigen in subacute sclerosing panencephalitis. Lancet i, 542.

    Article  Google Scholar 

  • Connolly, J. H., Allen, Ingrid, Hurwitz, L. J. and Millar, J. H. D. 1968. Subacute sclerosing panencephalitis. Quart. J. Med. 37, 625.

    PubMed  CAS  Google Scholar 

  • Dayan, A. D., Gostling, J. V. T., Greaves, J. L., Stevens, D. W. and Woodhouse, M. A. 1967. Evidence of a pseudomyxovirus in the brain in subacute sclerosing leucoencephalitis. Lancet i, 980.

    Article  Google Scholar 

  • Dayan, A. D. and Stokes, M. I. 1972. Immune complexes and visceral deposits of measles antigens in subacute sclerosing panencephalitis. Brit. Med. J., i, 374.

    Article  Google Scholar 

  • Freeman, J. M., Magoffin, R. L., Lennette, E. H. and Herndon, R. M. 1967. Additional evidence of the relation between subacute inclusion-body encephalitis and measles virus. Lancet ii, 129.

    Article  Google Scholar 

  • Greenfield, J. G. 1950. Encephalitis and encephalomyelitis in England and Wales during the last decade. Brain, 73, 141.

    Article  PubMed  CAS  Google Scholar 

  • Herndon, R. M. and Rubinstein, L. J. 1968. Light and electron microscopy observations on the development of viral particles in the inclusions of Dawson’s encephalitis (subacute sclerosing panencephalitis). Neurology (Minneap.), 18, Part 2, 2.

    Google Scholar 

  • Horta-Barbosa, L., Fuccillo, D. A., Sever, J. L. and Zeman, W. 1969. Subacute sclerosing panencephalitis: Isolation of measles virus from a brain biopsy. Nature (London), 221, 974.

    Article  CAS  Google Scholar 

  • Horta-Barbosa, L., Fucillo, D. A., Hamilton, R., Truab, R., Ley, A. and Sever, J. L. 1970. Some characteristics of SSPE measles virus. Proc. Exp. Biol. Med., 134, 17.

    CAS  Google Scholar 

  • Huang, Alice S. and Baltimore, D. 1970. Defective viral particles and viral disease processes. Nature (London), 226, 325.

    Article  CAS  Google Scholar 

  • Lennette, E. H., Magoffin, R. L. and Freeman, J. M. 1968. Immunological evidence of measles virus as an aetiological agent in subacute sclerosing panencephalitis. Neurology (Minneap.), 18, Part 2, 2.

    Google Scholar 

  • Lombroso, C. T. 1968. Remarks on the EEG and movement disorder in SSPE. Neurology (Minneap.), 18, Part 2, 2.

    Google Scholar 

  • Payne, F. E., Baublis, J. V. and Itabashi, N. N. 1969. Isolation of measles virus from cell cultures of brain from a patient with subacute sclerosing panencephalitis. New Eng. J. Med., 281, 585.

    PubMed  CAS  Google Scholar 

  • Perier, O., Thiry, L, Vanderhaeghen, J. J. and Pelc, S. 1968. Attempts at experimental transmission and electron microscopic observations in subacute sclerosing panencephalitis. Neurology (Minneap.), 18, Part 2, 2.

    Google Scholar 

  • Schneck, S. A. 1968. Vaccination with measles and central nervous system disease. Neurology (Minneap.) 18, Part 2, 2.

    Google Scholar 

  • Tellez-Nagel, I. and Harter, D. H. 1966. Subacute sclerosing leucoencephalitis: Ultrastructure of intranuclear and intracytoplasmic inclusions. Science, 154, 899.

    Article  Google Scholar 

  • Zeman, W. and Kolar, O. 1968. Reflections on the etiology and pathogenesis of subacute sclerosing panencephalitis. Neurology (Minneap.) 18, Part 2, 2.

    Google Scholar 

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A communication to the Section of Paediatrics, Royal Academy of Medicine in Ireland, 4th February 1972

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Dinn, J.J., McCaughey, W.T.E. & Rees, J.P.R. Subacute sclerosing panencephalitis: Report of two cases. Ir J Med Sci 142, 189–197 (1973). https://doi.org/10.1007/BF02950010

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