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A controlled trial of potensan forte (“aphrodisiac” and testosterone combined) in impotence

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Summary

  1. 1.

    A double-blind clinical trial of Potensan Forte (comprising methyl testosterone, yohimbine, pemoline and strychnine) against placebo, two months each assigned randomly, was carried out on 25 primarily impotent males. Pre-trial, urinary testosterone was assayed in 15 subjects.

  2. 2.

    Although there was an unmistakeable trend towards improvement on Potensan Forte which reached a maximum on 2 capsules t.i.d., this reached statistical significance on only one variable and was comparatively short lasting; at a one year follow-up the patients were worse than at referral.

  3. 3.

    There was no relationship between pre-trial androgen status and the treatment response. It was suggested that improvement was “nonspecific” being due to the non-steroid components of Potensan Forte, especially the C.N.S. stimulants pemoline and strychnine.

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Authors and Affiliations

  1. Department of Psychiatry, University of Edinburgh, Edinburgh

    A. J. Cooper & C. G. Smith

  2. Medical Research Council, Clinical Endocrinology Research Unit, Edinburgh

    A. A. A. Ismail & J. A. Loraine

Authors
  1. A. J. Cooper
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  2. C. G. Smith
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  3. A. A. A. Ismail
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  4. J. A. Loraine
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Additional information

Reprints from A. A. A. Ismail, 2 Forrest Road, Edinburgh 2, Scotland

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Cooper, A.J., Smith, C.G., Ismail, A.A.A. et al. A controlled trial of potensan forte (“aphrodisiac” and testosterone combined) in impotence. Ir J Med Sci 142, 155–161 (1973). https://doi.org/10.1007/BF02950005

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  • DOI: https://doi.org/10.1007/BF02950005

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