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Modeling and simulation of lactic acid fermentation with inhibition effects of lactic acid and glucose

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Abstract

An unstructured mathematical model for lactic acid fermentation was developed. This model was able to predict the inhibition effects of lactic acid and glucose and was confirmed to be valid with various initial concentrations of lactic acid and glucose. Simulation of energy production was made using this mathematical model, and the relationship between the kinetics of energy metabolism and lactic acid production was also analyzed.

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Authors and Affiliations

  1. State Key Lab of Microbial Technology, School of Life Science, Shandong University, 250100, Jinan, China

    Jian-qiang Lin

  2. Department of Biological Engineering, ERC for Advanced Bioseparation Technology, Inha University, 402-751, Incheon, Korea

    Sang-Mok Lee & Yoon-Mo Koo

Authors
  1. Jian-qiang Lin
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  2. Sang-Mok Lee
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  3. Yoon-Mo Koo
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Correspondence to Yoon-Mo Koo.

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Lin, Jq., Lee, SM. & Koo, YM. Modeling and simulation of lactic acid fermentation with inhibition effects of lactic acid and glucose. Biotechnol Bioproc E 9, 52–58 (2004). https://doi.org/10.1007/BF02949322

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  • DOI: https://doi.org/10.1007/BF02949322

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