Abstract
Objective: To compare the preventive effect of treatment with different methods of traditional Chinese medicine(TCM) for myocardial ischemia caused by coronary artery ligation in diabetic rats.Methods:Animal models established by streptozotocin plus coronary artery ligation were treated by modified Taoren Chengqi Decoction (MTRCQD) and different combinations of its ingredients respectively, and the effects on ischemia area, occurrence of arrhythmia, T-wave in ECG and 2 hrs post-operational survival rate were observed and compared.Results: MTRCQD and different combinations of its ingredients could reduce the area of ischemia and elevate survival rate significantly (P<0.05–0.01), especially in the group treated with MTRCQD plus leech. Improvement of T-wave was shown in the groups treated with MTRCQD or with MTRCQD plus leech.Conclusion: TCM treatment of invigorating Qi, nourishing Yin, purging Heat and activating blood circulation is an effective treatment for diabetic coronary heart disease.
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Li, S., Xiong, M., Lin, A. et al. Comparative study on effects of different treatments in preventing myocardial ischemia caused by coronary artery ligation in diabetic rats. CJIM 6, 290–294 (2000). https://doi.org/10.1007/BF02947384
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DOI: https://doi.org/10.1007/BF02947384