Abstract
Objective: To evaluate the therapeutic effect of Juanxiao Tablet (JXT) in treating asthma.Methods: Clinical observation on 447 cases of asthma was done in double- or single-blinded control method, and the therapeutic effect and safety of JXT were analysed. The effect of JXT in anti-asthma, expectorant, antisepsis, hypoxia tolerance was studied, and its acute and chronic toxicity was also examined.Results: The clinical control rate in patients treated with JXT was 38.2 %, the markedly effective rate 31.2% and the total effective rate 93.4 %, whereas in patients treated with Oleum Vitex Negundo, the respective rates were 13.3 %, 20.0 % and 68.5%. Results of pulmonary function and IgE measurement were consistent with clinical effect. Experimental study showed that JXT has the actions of anti-asthma, expectorant, antisepsis and hypoxia tolerance enhancement, with its LD50(40.48 ± 5.17) g/kg.Conclusion: JXT is a new Chinese herbal preparation of good effect, with less toxic-side effect for asthma treatment.
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Hong, G., Zhang, Y., Huang, J. et al. Clinical and experimental studies on treatment of asthma with Juanxiao tablet. CJIM 6, 271–275 (2000). https://doi.org/10.1007/BF02947378
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DOI: https://doi.org/10.1007/BF02947378