Skip to main content
Log in

Analyses of red fermented rice (angkak) and report of a newMonascus metabolite

  • Published:
Mycotoxin Research Aims and scope Submit manuscript

Abstract

A HPLC-based method for the analysis of red fermented rice and results obtained with it are presented. Formation of citrinin, red, orange and yellow pigments byMonascus depends on the culture substrate. Citrinin and some pigments are decomposed by heat. A newMonascus metabolite, monascodilone, its structure and preliminary data on its toxicity are reported.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ma J, Li Y, Ye Q, Li J, Hua Y, Ju D, Zhang D, Cooper R, Chang M (2000) Constituents of red yeast rice, a traditional food and medicine.J. Agric. Food Chem., 48: 5220–5225.

    Article  PubMed  CAS  Google Scholar 

  2. Juzlová P Martinková L, Kren V (1996) Secondary metabolites of the fungusMonascus- a review.J. Industrial Microbiol, 16: 163–170.

    Article  Google Scholar 

  3. Martinková L, Juzlová P, Vesely D (1995) Biological activity of polyketide pigments produced by the fungusMonascus.J. Appl. Microbiol., 79: 609–616

    Article  Google Scholar 

  4. Blanc PJ, Loret MO, Goma G (1995) Production of citrinin by various species ofMonascus.Biotechnol. Lett., 17: 291–294.

    Article  CAS  Google Scholar 

  5. Nozaki H, Date S, Kondo H, Kiyohara H, Takaoka D, Tada T, Nakayama M (1991) Ankalactone, a new α ß-unsaturated ϰ-lactone fromMonascus anka.Agric. Biol. Chem., 55: 899–900.

    CAS  Google Scholar 

  6. Endo A, Komagata D, Shimada H (1986) Monacolin M, a new inhibitor of cholesterol biosynthesis.J. Antibiot., 39: 1670–1673.

    PubMed  CAS  Google Scholar 

  7. Martinková L, Patáková-Juzlová P, Kren V, Kucerová Z, Havlicek V, Olsovsky P, Hovorka O, Rihová B, Vesely D, Veselá D, Ulrichová, J Prikrylová V (1999) Biological activities of oligoketide pigments ofMonascus purpureus.Food Add. Contam., 16: 15–24.

    Article  Google Scholar 

  8. Hossain CF, Okuyama E, Yamazaki M (1996) A new series of coumarin derivatives having monoamine oxidase inhibitory activity fromMonascus anka.Chem. Pharm. Bull, 44: 1535–1539.

    PubMed  CAS  Google Scholar 

  9. Wang IK, Lin-Shiau SY,. Chen PC, Lin JK (2000) Hypotriglyceridemic effect of Anka (a fermented rice product ofMonascus sp.) in rats.J. Agric. Food Chem., 48: 3183–3189.

    Article  PubMed  CAS  Google Scholar 

  10. Fink-Gremmels J, Dresel J, Leistner L (1991) Use of Monascus extracts as an alternative to nitrite in meat products.Fleischwirtschaft 71: 1184–1186

    CAS  Google Scholar 

  11. Wild D (2000) Rotschimmelreis: Inhaltsstoffe und Anwendung in Fleischerzeugnissen.BAFF Mitteilungsblatt, 39, Nr. 148, 701–706

    Google Scholar 

  12. Wild D, Tóth G, Humpf H-U (2002) A new Monascus metabolite isolated from red yeast rice (angkak, red koji).J. Agric. Food Chem., 50: 3999–4002

    Article  PubMed  CAS  Google Scholar 

  13. Hanelt M, Gareis M, Kollarcik B (1994) Cytotoxicity of mycotoxins evaluated by the MTT cell culture assay.Mycopathologia, 128: 167–174

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wild, D., Gareis, M. & Humpf, H.U. Analyses of red fermented rice (angkak) and report of a newMonascus metabolite. Mycotox Res 18 (Suppl 2), 212–216 (2002). https://doi.org/10.1007/BF02946098

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02946098

Key words

Navigation