Skip to main content
Log in

Moniliformin production in the genusFusarium

  • Published:
Mycotoxin Research Aims and scope Submit manuscript


More than 600Fusarium strains were screened for their ability to produce moniliformin in vitro. They represented 90 species and 15 sections (without sectionPseudomicrocera). A simple TLC-method (agar plug method) was tested for its applicability to detect moniliformin in fungal cultures. It revealed moniliformin production in 146 strains representing 32 species, all belonging to sections of which the teleomorph is known to beGibberella. The results by and large agree with earlier published data. However, some species did not show any moniliformin production in contrast to other reports. Furthermore, moniliformin production is reported for the first time in two known and in two not yet described species. 58 species were unable to generate the toxin. The results support the importance to include mycotoxin production of fungi as a criterion in a polyphasic taxonomy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Cole RJ, Kirksey JW, Cutler HG, Doupnik BL, Peckham JC (1973) Toxin fromF. moniliforme: effects on plants and animals. Science 179: 1324–1326

    Article  PubMed  CAS  Google Scholar 

  2. Scott PM, Abbas HK, Mirocha CJ, Lawrence GA, Weber D (1987) Formation of moniliformin byFusarium sporotrichioides andFusarium culmorum. Appl Environ Microbiol 53: 196–197

    PubMed  CAS  Google Scholar 

  3. Chelkowski J, Zawadzki M, Zaikowski P, Logrieco A, Bottalico A, (1990) Moniliformin production byFusarium species. Mycotoxin Res 6: 41–45

    CAS  Google Scholar 

  4. Marasas WFO, Thiel PG, Sydenham EW, Rabie CJ, Lübben A, Nelson PE (1991) Toxicity and moniliformin production by four recently described species ofFusarium and two uncertain taxa. Mycopathologia 113: 191–197

    Article  PubMed  CAS  Google Scholar 

  5. Cole RJ, Cox RH (1981) Handbook of toxic fungal metabolites: S. 894–897. Academic Press Inc., New York

    Google Scholar 

  6. Abbas HK, Mirocha CJ, Gunther R (1991) Production of zearalenone, nivalenol, moniliformin, and wortmannin from toxigenic cultures ofFusarium obtained from pasture soil samples collected in New Zealand. Mycotoxin Res 7: 53–60

    CAS  Google Scholar 

  7. Filtenborg O, Frisvad JC, Svendsen JA (1983) Simple screening method for molds producing mycotoxins in pure cultures. Appl Environ Microbiol 45: 581–585ba]

    PubMed  CAS  Google Scholar 

  8. Nirenberg HI (1976) Untersuchungen über die morphologische und biologische Differenzierung in der Fusarium-Sektion Liseola. Mitt Biol Bundesanst Land- Forstwirtsch, Berlin-Dahlem 169

    Google Scholar 

  9. Scott PM, Lawrence GA (1987) Liquid chromatographic determination and stability of theFusarium mycotoxin moniliformin in cereal grains. J Assoc Off Anal Chem 70: 850–853

    PubMed  CAS  Google Scholar 

  10. Kriek NPJ, Marasas WFO, Steyn PS, van Rensburg SJ, Steyn M (1977) Toxicity of a moniliformin-producing strain ofFusarium moniliforme van subglutinans isolated from maize. Food Cosmet Toxicol 15: 579–587

    Article  PubMed  CAS  Google Scholar 

  11. Marasas WFO, Leistner L, Hofmann G, Eckhardt C (1979) Occurence of toxigenic strains ofFusarium in maize and barley in Germany. Europ J Appl Microbiol Biotechnol 7: 289–305

    Article  CAS  Google Scholar 

  12. Rabie CJ, Marasas WFO, Thiel PG, Lübben A, Vleggaar R (1982) Moniliformin production and toxicity of differentFusarium species from southern Africa. Applbiol 43: 517–521

    CAS  Google Scholar 

  13. Marasas WFO, Thiel PG, Rabie CJ (1986) Moniliformin production inFusarium sectionLiseola. Mycologia 78: 242–247

    Article  CAS  Google Scholar 

  14. Schütt F, Nirenberg HI, Deml G (1998) Moniliformin production within theLiseola- Dlaminia complex. Accepted for publication by Cer Res Communic

  15. Nirenberg HI and Aoki T (1997)Fusarium nisikadoi, a new species from Japan. Mycoscience 38: 329–333

    Article  Google Scholar 

  16. Nirenberg HI, O’Donnell K, Kroschel J, Adrianaivo AP, Frank JM, Mubatanhema W (1998) Two new species ofFusarium: Fusarium brevicatenulatum from the noxious weedStriga asiatica in Madagascar andFusarium pseudoanthophilum from Zeamays in Zimbabwe. Mycologia 90: 459–464

    Article  Google Scholar 

  17. Nirenberg HI and O’Donnell K (1998) NewFusarium species and combinations within theGibberella fujikuroi species complex. Mycologia 90: 434–458

    Article  Google Scholar 

  18. Logrieco A, Bottalico A, Ricci V (1990) Occurence ofFusarium species and their mycotoxins in cereal grains from some Mediterranean countries. Phytopath Medit 29: 81–89

    Google Scholar 

  19. Hussein H, Baxter M, Andrew IG, Franich RA (1991) Mycotoxin production byFusarium species isolated from New Zealand maize fields. Mycopathologia 113: 35–40

    Article  PubMed  CAS  Google Scholar 

  20. Rabie CJ, Luebben A, Louw AI, Rathbone EB, Steyn PS, Vleggaar R (1978) Moniliformin, a mycotoxin fromFusarium fusarioides. J Agrie Fd Chem 26: 375- 379

    Article  CAS  Google Scholar 

  21. Bottalico A, Visconti A, Solfrizzo M (1982) Production of moniliformin byFusarium species in Italy. Phytopath Medit 21: 105–106

    CAS  Google Scholar 

  22. Booth C (1971) The genusFusarium. CMI, Kew

  23. Gerlach W and Nirenberg HI (1982) The genusFusarium - a pictoral atlas. Mitt Biol Bundesanst Land-Forstwirtsch, Berlin-Dahlem 209: 1–406

    Google Scholar 

  24. Nelson PE, Toussoun TA, Marasas WFO ({dy1983})Fusarium species. An illustrated manual for identification. Pa. St. Univ. Press

  25. Burgess LW, Lidell CM, Summerell BA ({dy1988}) Laboratory Manual forFusarium Research. Univ. of Sydney

  26. Nirenberg HI (1989) Identification of fusaria occuring in Europe on cereals and potatoes. In: Chelkowski J (Ed)Fusarium: Mycotoxins, Taxonomy and Pathogenicity. Elsvier Science Publishers BV, Amsterdam: 179–193

    Google Scholar 

  27. Nirenberg HI (1990) Recent advances in the taxonomy ofFusarium. Studies in Mycology 32: 91–101

    Google Scholar 

  28. Sharman M, Gilbert J, Chelkowski J (1991) A survey of the occurence of the mycotoxin moniliformin in cereal samples from sources worldwide. Fd Add Contam 8: 459–466

    CAS  Google Scholar 

  29. Adler A, Lew H, Brodacz W, Edinger W, Oberforster M (1995) Occurence of moniliformin, desoxynivalenol, and zearalenone in durum wheat (Triticum durum Desf.). Mycotoxin Res 11: 9–15

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and permissions

About this article

Cite this article

Schütt, F., Nirenberg, H.I. & Demi, G. Moniliformin production in the genusFusarium . Mycotox Res 14, 35–40 (1998).

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: