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Basic therapy for rheumatoid arthritis: Nonsteroidal anti-inflammatory drugs

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Comprehensive Therapy


Nonsteroidal anti-inflammatory drugs (NSAIDs) are often the initial treatment for rheumatoid arthritis. NSAID-induced inhibition of cyclooxygenase-2 (COX2) and cyclooxygenase-1 appears to correlate with clinical efficacy and toxicity, respectively. Newer NSAIDs with greater COX2 selectivity offer the promise of less toxic therapy.

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Daoud, K.F., Jackson, C.G. & Williams, H.J. Basic therapy for rheumatoid arthritis: Nonsteroidal anti-inflammatory drugs. Compr Ther 25, 427–433 (1999).

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