Abstract
Frequency response of the glucose sensor based on the immobilized glucose oxidase membrane was investigated experimentally by giving the sinusoidal change of glucose concentration to the glucose sensor and observing its output signal. Observed values of gains and phase lags of the frequency response of the glucose sensor followed the frequency response model of the first-order with dead time; The time constant and also the dead time were estimated and found to decrease as the amount of enzyme immobilized in the membrane increased and the thickness of the membrane decreased.
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References
Kim C. (1995), Dynamic behavior of biosensors based on immobilized enzyme membrane, Master’s thesis, Fukuoka Institute of Technology, Fukuoka, Japan.
Gondo, S., Osaki, T., Koya, H., and Morishita, M. (1981),Artificial Organs 5, 732–734.
Morishita, M., Osaki, T., and Gondo, S. (1981),Kagaku Kogaku Ronbunshu 7, 320–323.
Gondo, S., Osaki, T., and Morishita, M., (1981)J. Mol. Catalysis 12, 365–374.
Gondo, S. and Morishita, M. (1986),Ann. NY Acad. Sci. 469, 190–193.
Gondo, S. and Morishita, M. (1981),Artificial Organs 5, 307,308.
Gondo, S. and Morishita, M. (1983),Ann. NY Acad. Sci. 413, 225–227.
Ceaglske, N. (1956),Automatic Process Control for Chemical Engineers. John Wiley, New York.
Kuester, J. L. and Mize, J. H. (1973),Optimization Techniques with Fortran. McGraw-Hill, New York.
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Gondo, S., Kim, C., Morishita, M. et al. Frequency response of the glucose sensor based on immobilized glucose oxidase membrane. Appl Biochem Biotechnol 57, 877–884 (1996). https://doi.org/10.1007/BF02941768
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DOI: https://doi.org/10.1007/BF02941768