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A techno-economic assessment of the pretreatment and fractionation steps of a biomass-to-ethanol process

  • Session 4 Process Economics and Commercialization
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Abstract

It is generally recognized that the front-end (pretreatment, fractionation, enzymatic hydrolysis) steps of a lignocellulose-to-ethanol process are both technologically immature and represent a large component (∼60%) of the total product cost. In the past, we have tried to itemize the process steps and equipment for a complete plant. It was evident that, owing to the complexity and interrelated nature of this process, it was difficult to determine the influence of even minor changes to the process on the overall production cost of the product. We had originally developed a techno-economic model, based on spreadsheets, as a computational and assessment tool. However, our more recent work, which has looked at various process options such as hardwood vs softwoods, SO2 pretreatment of softwoods, and enzyme recycling, indicated that the model required greater flexibility if it was to assess a “generic” biomass-to-ethanol process. The model is currently being modified to address both the flexibility issues, through the incorporation of flowsheeting concepts, as well as including the most recent work on the various process options. In this article, we have described some of the pretreatment and fractionation issues that are being addressed in the updated model.

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References

  1. Nguyen, Q. and Saddler, J. N. (1991),Biores. Technol. 35, 275–282.

    Article  CAS  Google Scholar 

  2. Zacchi, G., Skoog, K., and Hahn-Hagerdahl, B. (1988),Biotechnol. Bioeng. 32, 460–466.

    Article  CAS  Google Scholar 

  3. Douglas, L. J. (1989), Main report, vol. 1. Report for DSS Contract No. 23283-6-6091.

  4. Holtzapple, M. T., Lundeen, J. E., Sturgis, R., Lewis, J. E., and Dale, B. E. (1992),Appl. Biochem. Biotechnol. 34/35, 521.

    Article  Google Scholar 

  5. Galbe, M. and Zacchi, G. (1986),Biotechnol. Bioeng. Symp. 17, 97.

    CAS  Google Scholar 

  6. Saddler, J. N., Ramos, L. P., and Breuil, C. (1993), inBioconversion of Forest and Agricultural Plant Wastes, Saddler, J. N., ed., C. A. B. International, London, UK, pp. 73–92.

    Google Scholar 

  7. Foody, P. (1980), Optimization of Steam Explosion Pretreatment. Final Report for Contract No. DE-AC-02-79-ETZ3050, Submitted to U. S. Department of Energy Fuels from Biomass Program.

  8. Mamers, H. and Menz, D. N. J., (1984), Appita37, 644–649.

    CAS  Google Scholar 

  9. Dekker, R. F., Karageorge, H., and Wallis, A. F. A. (1987),Biocatalysis 1, 45–59.

    Google Scholar 

  10. Brownell, H. H. (1989), Progress Report for the Project No. 04-53-12-402. Forintek Canada: Ottawa, Ontario.

    Google Scholar 

  11. Eklund, R., Galbe, M., and Zacchi, G. (1990),Enzyme Microb. Technol. 12, 225–228.

    Article  CAS  Google Scholar 

  12. Tenrud, I. E., Theander, O., Torneport, L., and Vallander, L. (1989),Enzyme Microb. Technol. 11, 500–506.

    Article  Google Scholar 

  13. Beltrame, P. L., Carniti, P., Visciglio, A., Focher, B., and Marzetti, A. (1992),Biores. Technol. 39, 165–171.

    Article  CAS  Google Scholar 

  14. Marchal, R., Ropars, M., and Vandecasteele, J. P. (1986),Biotechnol. Lett. 8, 365–370.

    Article  CAS  Google Scholar 

  15. Dekker, R. F. H. and Wallis, A. F. A. (1983),Biotechnol. Bioeng. 25, 3027–3048.

    Article  CAS  Google Scholar 

  16. Morjanoff, P. J. and Gray, P. P. (1987),Biotechnol. Bioeng. 29, 733–741.

    Article  CAS  Google Scholar 

  17. Brownell, H. H. and Saddler, J. N. (1987),Biotechnol. Bioeng. 29, 228–235.

    Article  CAS  Google Scholar 

  18. Brownell, H. H. and Saddler, J. N. (1984),Biotechnol. Bioeng. Symp. 14, 55–68.

    CAS  Google Scholar 

  19. Brownell, H. H., Yu, E. K. C., and Saddler, J. N. (1986),Biotechnol. Bioeng. 28, 792–801.

    Article  CAS  Google Scholar 

  20. Mackie, K. L., Brownell, H. H., West, K. L., and Saddler, J. N. (1985),J. Wood. Chem. Technol. 5, 405–425.

    Article  CAS  Google Scholar 

  21. Schwald, W., Breuil, C., Brownell, H. H., Chan, M., and Saddler, J. N. (1989),Appl. Biochem. Biotechnol. 8, 543–560.

    Google Scholar 

  22. Dekker, R. F. H., Karageorge, H., and Wallis, A. F. A. (1987),Biocatalysis 1, 45–59.

    Google Scholar 

  23. Ramos, L. P., Breuil, C., Kushner, D. N., and Saddler, J. N. (1992),Holzforschung 46, 149–154.

    CAS  Google Scholar 

  24. Eklund, R., (1994), Ph.D. thesis, University of Lund, Sweden.

    Google Scholar 

  25. Schwald, W., Smaridge, T., Chan, M., Breuil, C., and Saddler, J. N. (1989),Enzyme Systems for Lignocellulosic Degradation, Coughlan, M. P., ed., Elsevier, New York, pp. 231–242.

    Google Scholar 

  26. Clark, T. A. and Mackie, K. L. (1987),J. Wood Chem. Technol. 7, 373–403.

    Article  CAS  Google Scholar 

  27. Eklund, R., Galbe, M., and Zacchi, G. (1988), The VIII international symposium on alcohol fuels, Tokyo, p. 101.

  28. Grohmann, K., Torget, R., and Himmel, M. (1985),Biotechnol. Bioeng. Symp. 15, 59–80.

    Google Scholar 

  29. Baker, A. J., Millet, M. A., and Sattler, L. D. (1975),Cellulose Technol. Res. ACS Symp. Series10, 75–105.

    CAS  Google Scholar 

  30. Chum, H. L., Johnson, D. K., Black, S. K., Baker, J., Grohmann, K., Sarkanen, K. V., Wallace, K., and Schroeder, H. A. (1988),Biotechnol. Bioeng. 31, 643–649.

    Article  CAS  Google Scholar 

  31. Grethlein, H. E. (1985),Bio/Technology 3, 155–160.

    Article  CAS  Google Scholar 

  32. Stone, J., Scallan, A., Donefer, E., and Ahlgren, E. (1969),Adv. Chem. Ser. 95, 219–241.

    Article  CAS  Google Scholar 

  33. Ramos, L. P., Breuil, C., and Saddler, J. N. (1992),Appl. Biochem. Biotechnol. 34/35, 37–48.

    Article  Google Scholar 

  34. Schwald, W., Brownell, H. H., and Saddler, J. N. (1988),J. Wood Chem. Technol. 8, 543–560.

    Article  CAS  Google Scholar 

  35. Ingram, L. O., Conway, T., Clark, D. P., Sewell, G. W., and Preston, J. F. (1987),Appl. Environ. Microbiol. 53, 2420–2425.

    CAS  Google Scholar 

  36. Hahn-Hagerdahl, B., Hallborn, J., Jeppsson, H., Olsson, L., Skoog, K., and Walfridsson, M. (1993), inBioconversion of Forest and Agricultural Plant Residues, Saddler, J. N., ed., CAB International, UK, pp. 260–268.

    Google Scholar 

  37. Zhang, M., Eddy, C., Deanda, K., Finkelstein, M., and Picataggio, S. (1995),Science 267, 240–243.

    Article  CAS  Google Scholar 

  38. Saddler, J. N., Ramos, L. P., and Breuil, C. (1993), inBioconversion of Forest and Agricultural Plant Residues, Saddler, J. N., ed., CAB International, UK, pp. 260–268.

    Google Scholar 

  39. Galbe, M. (1994), Ph.D. thesis, University of Lund, Sweden, pp. 80–85.

    Google Scholar 

  40. Roberto, I. C., Lacis, L. S., Barbosa, M. F. S., and de Mancilha, I. M. (1991),Process Biochem. 26, 15–21.

    Article  CAS  Google Scholar 

  41. Fein, J. E., Tallim, S. R., and Lawford, G. R. (1984),Can. J. Microbiol. 30, 682–690.

    Article  CAS  Google Scholar 

  42. Frazer, F. R. and McCaskey, T. A. (1989),Biomass 18, 31–42.

    Article  CAS  Google Scholar 

  43. Wilson, J. J., Deschatelets, L., and Nishikawa, N. K. (1989),Appl. Microbiol. Biotechnol. 31, 592–596.

    Article  CAS  Google Scholar 

  44. Clark, T. A. and Mackie, K. L. (1984),J. Chem. Technol. Biotechnol. 34B, 101–110.

    CAS  Google Scholar 

  45. Buchert, J. K., Niemela, K., Puls, J., and Poutanen, K. (1990),Process Biochem. 25, 176–180.

    CAS  Google Scholar 

  46. Tran, A. V. and Chambers, R. P. (1986),Enzyme Microbial. Technol. 8, 439–444.

    Article  CAS  Google Scholar 

  47. Leonard, R. H. and Hajny, G. J. (1945),Ind. Eng. Chem. 37, 390–395.

    Article  CAS  Google Scholar 

  48. van Zyl, C., Prior, B. H., and du Preez, J. C. (1988),Appl. Biochem. Biotechnol. 17, 357–369.

    Article  Google Scholar 

  49. Yu, S., Wayman, M., and Parekh, S. K. (1987),Biotechnol. Bioeng. 29, 1144–1150.

    Article  CAS  Google Scholar 

  50. Beck, M. J. (1993), inBioconversion of Forest and Agricultural Plant Residues, Saddler, J. N., ed., CAB International, UK, pp. 211–229.

    Google Scholar 

  51. Olsson, L. and Hahn-Hagerdahl, B. (1993),Process Biochem. 28, 249–257.

    Article  CAS  Google Scholar 

  52. Schwald, W. (1987), Effect of Steam Treatment on the Components of Pretreated and Postreated Aspenwood, and Characterization of the Resulting Fractions. Forintek Internal Report, p. 7.

  53. Parekh, S. R., Parekh, R. S., and Wayman, M. (1987),Process Biochem. 22(3), 85–91.

    CAS  Google Scholar 

  54. Forintek Canada (1985), Pretreatment methods for enhancing conversion of lignocellulosic material to liquid fuel. ENFOR C-299, DSS File Number—54SS23216-3-6364.

  55. Brownell, H. H. (1987), Steam Pretreatment of Wood in Relation to Enzymatic Hydrolysis. Final Report for DSS Contract 05SR. 31926-4-5022.

  56. Sutcliffe, R., Breuil, C., Brownell, H. H., and Saddler, J. N. (1988), The Influence of Lignin Extraction Solvents on the Enzymatic Hydrolysis of Steam-Treated Aspenwood, poster presentation at the IEA Workshop on the Bioconversion of Lignocellulosics, June 12–16, Ottawa.

  57. Galbe, M. and Zacchi, G. (1991),Appl. Biochem. Biotechnol. 34/35, 93.

    Article  Google Scholar 

  58. Fan, L. T., Lee, Y.-H., and Beardmore, D. H. (1980),Biotechnol. Bioeng. 22, 177–199.

    Article  CAS  Google Scholar 

  59. Puri, V. P. (1984),Biotechnol. Bioeng. 26, 1219–1222.

    Article  CAS  Google Scholar 

  60. Sasaki, T., Tanaka, T., Nanbu, N., Sato, Y., and Kainuma, K. (1979),Biotechnol. Bioeng. 21, 1031–1042.

    Article  CAS  Google Scholar 

  61. Gharpuray, M. M., Lee, Y.-H., and Fan, L. T. (1983),Biotechnol. Bioeng. 25, 157–172.

    Article  CAS  Google Scholar 

  62. Grethlein, H. E. (1985),Bio/Technology 3, 155–160.

    Article  CAS  Google Scholar 

  63. Grous, W. R., Converse, A. O., and Grethlein, H. E. (1986),Enzyme Microb. Technol. 8, 274–280.

    Article  CAS  Google Scholar 

  64. Sinitsyn, A. P., Gusakov, A. V., and Vlasenko, E. Y. (1991),Appl. Biochem. Biotechnol. 30, 43–59.

    Article  CAS  Google Scholar 

  65. Stone, J. E., Scallan, A. M., Donefer, E., and Ahlgren, E. (1969),Adv. Chem. Ser. 95, 219–241.

    CAS  Google Scholar 

  66. Thompson, D. N., Chen, H. C., and Grethlein, H. E. (1992),Biores. Technol. 39, 155–163.

    Article  CAS  Google Scholar 

  67. Lee, D., Yu, A. H. C., Wong, K. K. Y., and Saddler, J. N. (1994),Appl. Biochem. Biotechnol. 45/ 46, 407–415.

    Article  Google Scholar 

  68. Puls, J., Poutanen, K., Korner, H.-U., and Viikari, L. (1985),Appl. Microbiol. Biotechnol. 22, 416–423.

    Article  CAS  Google Scholar 

  69. Miller, D., Sutcliffe, R., and Saddler, J. N. (1989), inTAPPI Proceedings of the International Symposium on Wood and Pulping Chemistry, Technical Association of the Pulp and Paper Industry, Atlanta, GA, pp. 9–11.

    Google Scholar 

  70. Wong, K. K. Y., Deverell, K. F., Mackie, K. L., Clark, T. A., and Donaldson, L. A. (1988),Biotechnol. Bioeng. 31, 447–456.

    Article  CAS  Google Scholar 

  71. Bertran, M. S. and Dale, B. E. (1985),Biotechnol. Bioeng. 27, 177–181.

    Article  CAS  Google Scholar 

  72. Sinitsyn, A. P., Gusakov, A. V., and Vlasenko, E. Y. (1991),Appl. Biochem. Biotechnol. 30, 43–59.

    Article  CAS  Google Scholar 

  73. Excoffier, G., Toussaint, B., and Vignon, M. R. (1991),Biotechnol. Bioeng. 38, 13081317.

    Article  Google Scholar 

  74. Ucar, G. and Fengel, D. (1988),Holzforschung 42, 141–148.

    CAS  Google Scholar 

  75. Clesceri, L. S., Sinitsyn, A. P., Saunders, A. M., and Bungay, H. R. (1985),Appl. Biochem. Biotechnol. 11, 433–443.

    Article  CAS  Google Scholar 

  76. Converse, A. O., Ooshima, H., Burns, D. S. (1990),Appl. Biochem. Biotechnol. 24/25, 67–73.

    Article  Google Scholar 

  77. Saddler, J. N., Brownell, H. H., Clermont, L. P., and Levitin, N. (1982),Biotechnol. Bioeng. 24, 1389–1402.

    Article  CAS  Google Scholar 

  78. Ramos, L. P. and Breuil, C., and Saddler, J. N. (1992),Appl. Biochem. Biotechnol. 34/35, 37–47.

    Article  Google Scholar 

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  1. Chair of Forest Products Biotechnology, Faculty of Forestry, University of British Columbia, #270-2357 Main Mall, V6T 1Z4, Vancouver, British Columbia, Canada

    David Gregg & John N. Saddler

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  1. David Gregg
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  2. John N. Saddler
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Gregg, D., Saddler, J.N. A techno-economic assessment of the pretreatment and fractionation steps of a biomass-to-ethanol process. Appl Biochem Biotechnol 57, 711–727 (1996). https://doi.org/10.1007/BF02941753

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