Summary
1. The outcome of pregnancies in mothers who either developed or were in contact with rubella during an epidemic in Dublin in 1956 is described and analysed.
2. Using the results of a previous survey of congenital abnormalities in the general population of Dublin for comparison it was found that the incidence in those mothers who had developed or been in contact with rubella was more than four times the expected level.
3. The incidence of congenital deformities in women who conracted the disease was nearly 10 times the expected level and in women who were exposed to infection but did not develop rubella about 2·5 times.
4. The risk of producing an abnormal baby was 2·5 times greater when the mother contracted the disease in the first trimester than in the second and third trimesters. In the former case the risk was 30 per cent.
5. The findings in this survey are compared with others in the literature.
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Coffey, V.P., Jessop, W.J.E. Rubella and incidence of congenital abnormalities. Ir J Med Sci 34, 1–11 (1959). https://doi.org/10.1007/BF02940489
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DOI: https://doi.org/10.1007/BF02940489