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Drug efficacy and side effects following different formulations of intravenous diazepam

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Summary

Intravenously injected diazepam in emulsion form (Diazemuls) was associated with significantly fewer painful injections and significantly less indirectly assessed phlebitis compared with the same drug with propylene glycol as a solvent (Valium). No differences in drug efficacy was noted between the 2 preparations.

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References

  • Ann-Marie Thorn-Alquist. 1977. Parenteral use of diazepam in an emulsion formulation. A clinical study. Acta Anaesth. Scand. 21, 400–404.

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Authors and Affiliations

  1. Department of Medicine and Gastroenterology, The Charitable Infirmary, Jervis Street, Dublin 1

    Mary Craig & J. F. Fielding

Authors
  1. Mary Craig
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  2. J. F. Fielding
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Craig, M., Fielding, J.F. Drug efficacy and side effects following different formulations of intravenous diazepam. Ir J Med Sci 151, 79–80 (1982). https://doi.org/10.1007/BF02940151

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  • DOI: https://doi.org/10.1007/BF02940151

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