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The effect of apple fibre on diabetic control and plasma lipids

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Summary

THE purpose of the study was to investigate the effect of apple fibre on diabetic control and on plasma lipid levels in non insulin dependent maturity onset diabetes mellitus. Twelve patients (8 females and 4 males) ingested 15g of apple fibre per day over a period of 7 weeks. There was a significant improvement in diabetic control, as reflected by a fall in mean fasting plasma glucose (P<0.05) and in percentage glycosylated haemoglobin (p<0.005). There was a 5% decrease in plasma cholesterol and 4% increase in HDL-cholesterol with no change in plasma triglyceride. These results suggest that apple fibre may be a useful adjuvant in the management of non insulin dependent maturity onset diabetic patients.

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References

  • Burnstein, M., Samaille, J. 1960. Sur en dosage rapide du cholesterol lie aux α aux β lipoproteins du serum. Clin. Chim. Acta. 5, 609–610.

    Article  Google Scholar 

  • Calvert, G. D., Graham, J. J., Mannik, T., Wise, P. H., Yeates, R. A. 1978. Effects of therapy on plasma high density lipoprotein cholesterol concentration in diabetes mellitus. Lancet ii, 66–68.

    Article  Google Scholar 

  • Ditzel, J., Kjaergaard, J. J. 1978. Haemoglobin A1 c concentrations after initial insulin treatment for newly discovered diabetes. Br. Med. J. i, 741–742.

    Google Scholar 

  • Durrington, P. N., Manning, A. P., Boulton, C. H, Hartog, M. 1976. Effect of pectin on serum lipids and lipoproteins, whole gut transit time and stool weight. Lancet ii, 394–396.

    Article  Google Scholar 

  • Gabbay, K. G., Hasty, K., Breslow, J. L., Ellison, R. C, Bunn, F. H., Gallop, I. M. 1977. Glycosylated haemoglobins and long term blood glucose control in diabetes mellitus. J. Clin. Endocrinol. Metab. 44, 859–864.

    PubMed  CAS  Google Scholar 

  • Gonen T., Rubenstein, A. H., Rochman, H., Tanaga, S. P., Horwitz, D. L. 1977. Haemoglobin A1: an indicator of the metabolic control of diabetic patients. Lancet i, 734–737.

    Article  Google Scholar 

  • Gordon, T., Castelli, W. P., Hjortland, M. C, Kannel, W., Dawber, T. R. 1977. High density lipoprotein as a protective factor against coronary heart disease. Am. J. Med. 62, 707–714.

    Article  PubMed  CAS  Google Scholar 

  • Gormley, T. R., Kevany, J., Egan, J. P., McFarlane, R. 1977. Effect of apples on serum cholesterol levels in humans. Ir. J. Fd. Sci. Technol. 1, 117–128.

    CAS  Google Scholar 

  • Jenkins, D. J. A., Leeds, A. R., Newton C., Cummings, J. A. 1975. Effect of pectin, guar gum and wheat fibre on serum cholesterol. Lancet i, 1116.

    Article  Google Scholar 

  • Jenkins, D. J. A., Wolever, T. M. S., Leeds, A. R., Gassull, M. A., Haisman, P., Dilawari, J., Goff, D. V., Metz, G. L., Alberti, G. M. M. 1978. Dietary fibres, fibre analogues and glucose tolerance: importance of viscosity. Br. Med. J. i, 1392–1394.

    Google Scholar 

  • Jenkins, D. J. A., Wolever, T. M. S., Nineham, R., Taylor, R., Metz, G. L., Bacon, S., Hockaday, T. D. R. 1979. Guar crispbread in the diabetic diet. Br. Med. J. ii, 1744–1946.

    Google Scholar 

  • Jenkins, D. J. A., Wolever, T. M. S., Taylor, R. H., Reynolds, D., Nineham, R., Hockaday, T. D. R. 1980. Diabetic glucose control lipids and trace elements on long-term guar. Br. Med. J. i, 1353–1354.

    Article  Google Scholar 

  • Keen, H., Rose, G. D. A., Boyns, D., Chlouverakis, A., Mistry, S. 1965. Blood sugar and arterial disease. Lancet ii, 505–508.

    Article  Google Scholar 

  • Kennedy, A. L, Lappin, T. R. J., Lavery, T. D., Hadden, D. R., Weaver, J. A., Montgomery, D. A. D. 1978. Relation of high density lipoprotein cholesterol concentration to type of diabetes and its control. Br. Med. J. ii, 1191–1194.

    Google Scholar 

  • Kiehm, T. G., Anderson, J. W., Ward K., 1976. Beneficial effect of a high carbohydrate high fibre diet on hyperglycaemic diabetic man. Am. J. Clin. Nutr. 29, 895–899.

    PubMed  CAS  Google Scholar 

  • Lopes-Virella, M. F., Stone, P. G., Colwell, J. A. 1977. Serum high density lipoprotein in diabetic patients. Diabetologia 13, 285–291.

    Article  PubMed  CAS  Google Scholar 

  • Michael B., Camejo, M., Jacobs, J., Parker, J., St. Cry, M., Ruderman, N. 1979. H.D.L. in diabetes Lancet i, 155.

    Article  Google Scholar 

  • Miller, N. E., Forde, H., Thelle, D. S., Mjos, D. 1977. High density lipoprotein and coronary heart disease: a prospective case control study. Lancet i, 965–968.

    Article  Google Scholar 

  • Nikkila, E. A. 1978. Metabolie regulation of plasma high density lipoprotein concentrations. Eur. J. Clin. Invest. 8, 111–113.

    Article  PubMed  CAS  Google Scholar 

  • Roschlau, P., Bernt, E., Gruber, W. 1975. Enzymatic determination of total cholesterol in serum using peroxidase as indicating enzyme. Clin. Chem. 21, 941.

    Google Scholar 

  • Siegel, S. 1956.Non parametric statistics for the behavioural sciences. McGraw Hill, pp. 75–83.

  • Simpson, R. W., Mann, J. I., Hockaday, T. D. R., Turner, R. C, Jelfs, R. 1979. Lipid abnormalities in untreated maturity onset diabetes and1 the effect of treatment. Diabetologia 16, 101–106.

    Article  PubMed  CAS  Google Scholar 

  • Stanton K., 1978. HDL cholesterol in diabetes and heart disease. Lancet ii, 638.

    Article  Google Scholar 

  • Stein, S. M., Horn, D. B. 1972. The estimation of plasma glycerol using a reaction rate analyser. Clin. Chi m. Acta. 39, 293–300.

    Article  CAS  Google Scholar 

  • Trowell, H. 1975. Dietary fibre hypothesis of the aetiology of diabetes mellitus. Diabetes 24, 762–764.

    PubMed  CAS  Google Scholar 

  • Welch, S. G., Boucher, J. 1978. A rapid micro scale method for the measurement of haemoglobin A1(a+b+c). Diabetologia 14, 209–211.

    Article  PubMed  CAS  Google Scholar 

  • Yudkin, J. S., Boucher, J., France, M. W., Swindlehurst, C. 1979. The relationship between concentrations of glycosylated haemoglobin and of serum high density lipoprotein cholesterol in diabetic patients. Clinical Science 56, 269–272.

    PubMed  CAS  Google Scholar 

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Based on P. D. Mayne’s Registrars Prize, Royal Academy of Medicine in Ireland, 1979.

We thank Miss O’Shaughnessy, dietitian, Federated Dublin Voluntary Hospitals, Comhlucht Siuicre Eireann Teo. for freeze drying the apples and Ceimici Teo for the alcohol used in the preparation of the dietary fibre.

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Mayne, P.D., McGill, A.R., Gormley, T.R. et al. The effect of apple fibre on diabetic control and plasma lipids. Ir J Med Sci 151, 36–41 (1982). https://doi.org/10.1007/BF02940140

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