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Wirkung von Deoxynivalenol (DON) auf den Magen-Darm-Trakt männlicher Läuferschweine

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Abstract

Following an experiment feeding Deoxynivalenol to growing pigs histological studies have been carried out to evaluate tissue damaging effects of DON. Pigs were fed with naturally contaminated wheat containing 4000 and 6000 µg DON/kg feed. A number of two animals was chosen from control and high exposed group, respectively. Samples of the gastrointestinal tract, liver and kidney were examined. Although, clear effects in feed consumption and weight gain could be realized, only one animal from the high exposed group showed focal alterations in tissues of the gastrointestinal tract.

Zusammenfassung

Im Rahmen eines Fütterungsversuches wurden weiterführende Untersuchungen hinsichtlich einer gewebeschädigenden Wirkung von Deoxynivalenol durchgeführt. Hierzu wurden Schweine mit natürlich kontaminiertem Weizen (4000 und 6000 µg DON/kg Futter) gefüttert. Zu Versuchsende wurden stichprobenartig jeweils zwei Tiere aus Kontroll- und hochbelasteter Gruppe herausgegriffen, deren Magen-Darm-Trakt sowie Leber und Niere histologisch beurteilt. Trotz der hohen Belastung der Tiere sowie deutlicher Effekte in Futteraufnahme und Gewichtsentwicklung ließ sich kein einheitliches Bild über das gewebeschädigende Potential dieses Toxins erstellen.

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Authors and Affiliations

  1. Institut für Tieremährung (450), Universität Hohenheim, Emil-Wolff-Str. 10, 70599, Stuttgart, Deutschland

    Dillenburger T, Lauber U & Drochner W

  2. Institut für Umwelt- und Tierhygiene sowie Tiermedizin, Fachgebiet Anatomie und Physiologie der Haustiere, Universität Hohenheim, Fruwirthstr. 35, 70599, Stuttgart, Deutschland

    Steffl M & Schweiger M

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  1. Dillenburger T
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  2. Lauber U
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  3. Steffl M
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  4. Schweiger M
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  5. Drochner W
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Dillenburger, T., Lauber, U., Steffl, M. et al. Wirkung von Deoxynivalenol (DON) auf den Magen-Darm-Trakt männlicher Läuferschweine. Mycotox Res 16 (Suppl 2), 162–165 (2000). https://doi.org/10.1007/BF02940027

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  • DOI: https://doi.org/10.1007/BF02940027

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