Summary
A HIGHLY sensitive radioimmunoassay for the detection of progesterone in human saliva is described. In a study of random matched samples there was a close correlation between salivary and serum concentrations of hormone (r = 0.82; p<01). During the normal menstrual cycle follicular phase values of salivary progesterone were approximately 100 pmol/l with a subsequent rise to a mean peak luteal phase value of 541 pmol/l. These results and the potential value of saliva as an alternative to conventional body fluids for hormone assays are discussed.
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Supported by a Royal Victoria Hospital Research Fellowship.
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Heasley, R.N., Thompson, W. Salivary progesterone measurements in the normal menstrual cycle. I.J.M.S. 155, 19–22 (1986). https://doi.org/10.1007/BF02939945
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DOI: https://doi.org/10.1007/BF02939945