Summary
Atracurium besylate was used in a patient with myasthenia gravis for muscle relaxation during transthoracic resection of a thymic tumour. The quality and duration of neuromuscular blockade and the rate of spontaneous recovery of neuromuscular function is described.
Similar content being viewed by others
References
Castleman, B. 1966. ‘The pathology of the thymus gland in myasthenia gravis’. Ann. N.Y. Acad. Sci. 135, 496–503.
Chappie, D. J. and Clarke, J. S. 1983. ‘Pharmacological action of breakdown products of atracurium and related substances’. Br. J. Anaesth. 55, suppl. 11–15.
Drachman, D. B. 1978. ‘Myastenia gravis’. New Eng. J. Med. 298, 136–142.
Drachman, D. B. 1978. ‘Myastenia gravis’. New Eng. J. Med. 298, 186–193.
Drachman, D. B., Adams, R. N., Josifec, L. F. and Self, S. G. 1982. ‘Functional activity of autoantibodies to acetylcholine receptors and the clinical severity of myasthenia gravis’. New Eng. J. Med. 307; 769–775.
Fambrough, D. M., Drachman, D. B. and Satyamuri, S. 1973. ‘Neuromuscular functions in myashenia gravis: decreased acetylcholine receptors. Science. 182, 293–295.
Foldes, F. F., Nagashima, H., Boros, M., Tassonyi, E., Fitzal, S. and Agoston, S. 1983. ‘Muscle relaxation with atracurium, vecuronium and duador under balanced anaesthesia’. Br. J. Anaesth. 55, Suppl. 97–103.
Rupp, S. M., Fahey, M. R. and Miller, R. D. 1983. ‘Neuromuscular and cardiovascular effects of atracurium during nitrous oxidefentanyl and nitrous oxide—insoflurane anaesthesia’. Br. J. Anaesth. 55, Suppl. 67–70.
Stenlake, J. B., Waith, R. D., Urwin, J., Dewarm, G. H. and Coker, G. G. 1983. ‘Atracurium: conception and inception’. Br. J. Anaesth. 55, Suppl 32–10.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Murphy, D.F., Magner, J.B. Neuromuscular blockade with atracurium besylate in a patient with myasthenia gravis. I.J.M.S. 155, 202–203 (1986). https://doi.org/10.1007/BF02939843
Issue Date:
DOI: https://doi.org/10.1007/BF02939843