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The gut as an endocrine organ

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References

  • Aguilar-Parada, E., Eisentraut, A. M. and Unger, R. H. 1969. Pancreatic glucagon secretion in normal and diabetic subjects. Amer. J. Med. Sci., 257, 415.

    Article  PubMed  CAS  Google Scholar 

  • Alford, F. P., Bloom, S. R., Nabarro, J. D. N., Hall, R., Besser, G. M., Coy, D. H., Kastrin, A. J. and Schally, A. V. 1974. Glucagon control of fasting glucose in man. Lancet, ii, 974.

    Article  Google Scholar 

  • Ardill, J., Montgomery, D. A. D. and Hadden, D. R. 1974. Gastrin in diabetes. Diabetologia, 10, 357.

    Google Scholar 

  • Brazeau, P., Vale, W., Burgus, N., Ling, N., Butcher, M., Rivier, J. and Guillemin, R. 1973. Hypothalamic polypeptide that inhibits the secretion of immunoreactive growth hormone, Science (Washington, D.C.), 179, 77.

    Article  CAS  Google Scholar 

  • Buchanan, K. D., Flanagan, R. W. J., Murphy, R. F., O’Connor, F. A. and Shahidullah, M. 1974. Immunological characterisation of glucagon-like immunoreactivity. Europ. J. Clin. Invest., 4, 326.

    Google Scholar 

  • Buchanan, K. D. and Mawhinne, W. A. A. 1973a. Glucagon release from isolated pancreas in streptozotocin-treated rats. Diabetes, 22, 797.

    PubMed  CAS  Google Scholar 

  • Buchanan, K. D. and Mawhinney, W. A. A. 1973b. Insulin control of glucagon release from insulin-deficient rat islets. Diabetes, 22, 801.

    PubMed  CAS  Google Scholar 

  • Chisholm, D. J., Young, J. D. and Lazarus, L. 1969. The gastrointestinal stimulus to insulin release. 1. secretin. J. Clin. Invest., 48, 1453.

    Article  PubMed  CAS  Google Scholar 

  • Conlon, J. M., Flanagan, R. W. J. and Murphy, R. F. 1975. An improved affinity chromatographic system for the purification of glucagon-like immunoreactivity (G.L.I.). Diabetologia, 11, 336.

    Google Scholar 

  • Flanagan, R. W. J., Buchanan, K. D. and Murphy, R. F. 1974. Specificity of antibodies in radioimmunoassay of glucagon. Diabetologia, 10, 365.

    Google Scholar 

  • Flanagan, R. W. J., Trimble, E. R., Conlon, J. M. and Murphy, R. F. 1975. Purification and characterisation of plasma glucagon-like immunoreactivity by immunoaffinity chromatography. Diabetologia, 11, 342.

    Google Scholar 

  • Gerich, J. E., Lorenzi, M., Schneider, V., Karam, J. H., Rivier, J., Guillemin, R. and Forsham, P. H. 1974. Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus. New Eng. J. Med., 291, 544.

    PubMed  CAS  Google Scholar 

  • Hadden, D. R., Montgomery, D. A. D., Skelly, R. J., Trimble, E. R., Weaver, J. A., Wilson, E. A. and Buchanan, K. D. 1975. Maturity onset diabetes mellitus: response to intensive dietary management. Brit. Med. J., iii, 276.

    Google Scholar 

  • Hayes, J. R., Ardill, J. and Buchanan, K. D. 1975. Gastrin and insulin release. Diabetologia, 11, 89.

    Article  PubMed  CAS  Google Scholar 

  • Henry, R. W., Flanagan, R. W. J. and Buchanan, K. D. 1975. Secretin: a new role for an old hormone. Lancet, ii, 202.

    Article  Google Scholar 

  • Henry, R. W., Ardill, J. and Buchanan K. D. 1975. Pancreatic and gut hormones in starvation diabetes. Diabetologia, 11, 349.

    Google Scholar 

  • Lazarus, N. R., Voyles, N. R., Devrim, S., Tanese, T. and Recant, L. 1968. Extra-gastrointestinal effects of secretin, gastrin and pancreozymin. Lancet, ii, 248.

    Article  CAS  Google Scholar 

  • McIntyre, M., Holdsworth, C. D. and Turner, D. S. 1965. Intestinal factors in the control of insulin secretion. J. Clin Endocrinol., 25, 1317.

    Article  CAS  Google Scholar 

  • Mallinson, C. N., Bloom, S. R., Warin, A. O., Salmon, P. R. and Cox, B. 1974. A glucagonoma syndrome. Lancet, ii, 1.

    Article  Google Scholar 

  • Muller, W. A., Faloona, G. R. and Unger, R. H. 1973. Hyperlucagonaemia in diabetic ketoacidosis. Its prevalence and significance. Amer. J. Med., 54, 52.

    Article  PubMed  CAS  Google Scholar 

  • Murphy, R. F., Buchanan, K. D. and Elmore, D. T. 1973. Isolation of glucagon-like immunoreactivity of gut by affinity chromatography on anti-glucagon antibodies coupled to Sepharose 4B. Biochim. Biophys. Acta, 303, 118.

    PubMed  CAS  Google Scholar 

  • O’Connor, F. A., Connon, J. J., Buchanan, K. D. and Shahidullah, M. 1976. Secretin and insulin: response to intraduodenal acid. Diabetologia (in press).

  • Ross, S. A., Brown, J. C. and Dupre, J. 1974. Effect of gastric inhibitory polypeptide on endocrine pancreas in normal and diabetic subjects. Diabetologia, 10, 384.

    Google Scholar 

  • Samols, E., Marri, G. and Marks, V. 1965. Promotion of insulin secretion by glucagon. Lancet, ii, 415.

    Article  Google Scholar 

  • Trimble, E. R., Montgomery, D. A. D. and Hadden, D. R. 1974. Change in pattern of glucagon response during OGTT before and six months after commencement of intensive dietary management of diabetes. Diabetologia, 10, 389.

    Google Scholar 

  • Trimble, E. R., Buchanan, K. D., Hadden, D. R., Montgomery, D. A. D. and Weaver, J. A. 1975. Hypersecretinaemia in maturity onset diabetes correctable by dietary measures. Diabetologia, 11, 380.

    Google Scholar 

  • Unger, R. H., Eisentraut, A. M., McCall, M. S. and Madison, L. L. 1961. Glucagon antibodies and an immunoassay for glucagon. J. Clin. Invest., 40, 1280.

    Article  PubMed  CAS  Google Scholar 

  • Unger, R. H., Ketterer, H., Dupre, J. and Eisentraut, A. M. 1967. The effects of secretin, pancreozymin and gastrin on insulin and glucagon secretion in anaesthetised dogs. J. Clin. Invest. 46, 630.

    PubMed  CAS  Google Scholar 

  • Williams, R. H. 1974. Text Book of Endocrinology, 5th edition, W. B. Saunders, Philadelphia, p. 542.

    Google Scholar 

  • Wise, J. K., Hendler, R. and Felig, P. 1973. Evaluation of alpha cell function by infusion of alanine in normal, diabetic and obese subjects. New Eng. J. Med., 288, 487.

    PubMed  CAS  Google Scholar 

  • Yalow, R. S. and Berson, S. A. 1961. Immunoassay of plasma insulin in man. Diabetes, 10, 339.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Medicine, Queen’s University, Belfast

    Keith D. Buchanan

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  1. Keith D. Buchanan
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The Graves Lecture, 1975.

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Buchanan, K.D. The gut as an endocrine organ. IJMS 145, 103–115 (1976). https://doi.org/10.1007/BF02938929

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