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High amount of dietary carbohydrate does not cause an adaptational increase of stimulated human pancreatic amylase secretion

  • Ralf-Marco Liehr
  • Maria-Elisabeth Herrmann
  • Carsten Emde
  • Rüdiger Hopert
  • Ernst-Otto Riecken
Article
  • 12 Downloads

Summary

In order to investigate whether the human pancreas is capable of adapting to a diet with high-carbohydrate, low-fat, and normal protein content, 10 healthy volunteers were given a defined elemental diet (60% of calories as carbohydrates, 22% as fat, and 18% as protein) for 7 d. For the next 7 d they received an elemental diet with a further increased carbohydrate content (76% of calories) and a decreased fat content (10% of calories). A complete secretin-pancreozymin test was carried out at the end of the first wk and at d 14. The results show that an increase in dietary carbohydrate does not provoke an adaptational response of stimulated secretion rates of amylase, trypsin, and chymotrypsin in humans, as expected from animal experiments.

Key Words

Amylase secretion adaptation elemental diet diet composition 

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Copyright information

© Humana Press Inc. 1989

Authors and Affiliations

  • Ralf-Marco Liehr
    • 1
  • Maria-Elisabeth Herrmann
    • 1
  • Carsten Emde
    • 1
  • Rüdiger Hopert
    • 1
  • Ernst-Otto Riecken
    • 1
  1. 1.Medizinische Klinik und PoliklinikKlinikum Steglitz der FU BerlinBerlin 45FRG

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