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Acute Wernickes Encephalopathy precipitated by glucose loading

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Four cases of acute Wernickes Encephalopathy in non-alcoholic, malnourished patients are described. In each case the administration of a glucose load precipitated a neurological crisis which was rapidly reversed by the administration of intravenous Thiamine. It is suggested that prophylactic Thiamine treatment therapy should be considered in the management of all malnourished patients.

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Watson, A.J.S., Walker, J.F., Tomkin, G.H. et al. Acute Wernickes Encephalopathy precipitated by glucose loading. I.J.M.S. 150, 301–303 (1981).

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