Acute Wernickes Encephalopathy precipitated by glucose loading

  • A. J. S. Watson
  • J. F. Walker
  • G. H. Tomkin
  • M. M. R. Finn
  • J. A. B. Keogh
Article

Summary

Four cases of acute Wernickes Encephalopathy in non-alcoholic, malnourished patients are described. In each case the administration of a glucose load precipitated a neurological crisis which was rapidly reversed by the administration of intravenous Thiamine. It is suggested that prophylactic Thiamine treatment therapy should be considered in the management of all malnourished patients.

References

  1. Blass, J. P., Gibon, G. E. 1977. New Eng. J. Med. 297, 1367.PubMedGoogle Scholar
  2. Cravioto, H., Korein, J., Silberman, J. 1961. Archs. Neurol. 4, 510.Google Scholar
  3. Drenick, E. J., Joven, C. B., Swendseid, M. E. 1966. New Eng. J. Med. 274, 1937.Google Scholar
  4. Ebels, E. J. 1978. Lancet ii, 781.CrossRefGoogle Scholar
  5. Harper, C. J. 1979. J. Neurol. Neurosurg. Psychiat. 42, 226.PubMedGoogle Scholar
  6. Nadel, A. M., Burger, P. C. 1976. J.A.M.A. 235, 2403.PubMedCrossRefGoogle Scholar
  7. Wallis, W. E., Willoughby, E., Baker, P. 1978. Lancet ii, 480.Google Scholar
  8. Zaporin, Z. Z., Nuves, W. T., Powell, R. C. 1965. J. Nutr. 85, 287.Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • A. J. S. Watson
    • 1
  • J. F. Walker
    • 1
  • G. H. Tomkin
    • 1
  • M. M. R. Finn
    • 1
  • J. A. B. Keogh
    • 1
  1. 1.Department of Medicine, Meath HospitalAdelaide Hospital and Trinity CollegeDublin

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