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Screening for amphetamine in human urine

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Summary

Arapid method is described for the detection and qualitative analysis of amphetamine in human urine by extracting the urine in alkaline ether and screening for amphetamine by gas liquid chromatography. By taking advantage of the difference in retention times for amphetamine and nicotine contained in the samples, a procedure was developed for screening four samples for the presence of amphetamine in each run through the chromatographic column. The method is sensitive and rapid in execution. Twenty-eight samples can easily be extracted, and screened on one machine in two days. The presence of amphetamine can be confirmed by forming the acetone-amphetamine derivative which can then be compared with a standard.

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Authors and Affiliations

  1. Department of Pharmacology, Trinity College, Dubiin

    P. J. Byrne, K. J. Foran, Joan T. Miller & C. W. M. Wilson

Authors
  1. P. J. Byrne
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  2. K. J. Foran
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  3. Joan T. Miller
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  4. C. W. M. Wilson
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Byrne, P.J., Foran, K.J., Miller, J.T. et al. Screening for amphetamine in human urine. I.J.M.S. 140, 4–10 (1971). https://doi.org/10.1007/BF02937767

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  • DOI: https://doi.org/10.1007/BF02937767

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