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Dispersion and holdup in a three-phase fluidized-bed bioreactor

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Abstract

Axial dispersion and phase holdup measurements were made using electroconductivity in a fermenting fluidized-bed bioreactor (FBR) and in a model nonfermenting three-phase FBR. Multiple axial conductivity probes were used to nonintrusively monitor the bed conductivity. The gas phase holdup was estimated from a ratio of the average bed conductivity and bulk conductivity. The solid fraction in the three-phase FBR can be estimated from the two-phase liquid-solid FBR. The response to a salt pulse was used to estimate the liquid axial dispersion coefficient. Particle Peclet numbers on the order of 10-2 were estimated as a function of flowrates and compared to literature correlations.

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Davison, B.H. Dispersion and holdup in a three-phase fluidized-bed bioreactor. Appl Biochem Biotechnol 20, 449–460 (1989). https://doi.org/10.1007/BF02936502

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  • DOI: https://doi.org/10.1007/BF02936502

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