Clinical observation on effect of Xiaoyu Zhixue Tablet on 104 patients with idiopathic multifocal bleeding and pletelet aggregation defect

Abstract

Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT).Methods: XZT mainly composed of Chinese medical herbs to replenish Qi and remove stasis was used to treat patients with idiopathic multifocal bleeding and platelet aggregation defect. Patients were divided into 2 groups, the TCM group (104 cases) treated with XZT, and the control group (84 cases) with vitamin C, K and P, adrenosin and/or artificial menstruation, for at least 4 months.Results: The hemostatic effective rate was 92.3% in the TCM group and 27.4% in the control group (P< 0.005), the recovery rate of platelet aggregation after 6 months’ therapy was 69.2% and only 1.8% respectively. The difference between the two groups was very significant (P < 0.005).Conclusion: XZT could regulate the hemostatic action and platelet aggregation