Abstract
A case of a coincident acute lymphoblastic leukemia and marked eosinophilia is presented. The clinical and pathological features of this case are discussed with special emphasis on the hypereosinophilic syndrome versus secondary hypereosinophilia that can be found to accompany ALL. Special immunological studies may be helpful in the diagnostic procedures.
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References
Hardy WR, Anderson RE: The hypereosinophilic syndromes.Ann Intern Med 68, 1220–1229 (1968).
Spry CJF: The hypereosinophilic syndrome: Clinical features, laboratory findings and treatment.Allergy 37, 539–551 (1982).
Bush RK, Geller M, Busse WW, Flaherty DK, Dickie HA: Response to corticosteroids in the hypereosinophilic syndrome: association with increased serum IgE levels.Arch Intern Med 138, 1244–1246 (1978).
Schooley RT, Parrillo JE, Wolff SM, Fauci AS: Management of the idiopathic hypereosinophilic syndrome. In Mahmoud AAF, Austen KF (eds):The Eosinophil in Health and Disease, pp. 323–339. New York, Grune & Stratton (1980).
Huang CS, Gomez GA, Kohno SI, Sokal JE, Sandberg AA: Chromosomes and causation of human cancer and leukemia. XXXIV. A case of ‘hypereosinophilic syndrome’ with unusual cytogenetic findings in a chloroma, terminating in blast transformation and CNS leukemia.Cancer 44, 1284–1289 (1979).
Beeson PB, Bass DA: The eosinophil. In Smith LH (ed):Major Problems in Internal Medicine. XIV. Philadelphia, Saunders (1977).
Catovsky D, Bernasconi C, Verdonck PFet al: The association of eosinophilia with lymphoblastic leukemia or lymphoma: A study of seven patients.Br J Haematol 45, 523–554 (1980).
Hokland P, Nadler LM, Griffin JD, Schlossmann SF, Ritz J: Purification of cALLa-positive cells from normal human bone marrow.Blood 64, 662–666 (1984).
Troxell ML, Mills GM, Allen RC: The hypereosinophilic syndrome in acute lymphocytic leukemia.Cancer 54, 1058–1061 (1984).
Nelken RP, Stockman JA, III: The hypereosinophilic syndrome in association with acute lymphoblastic leukemia.J Pediatr 89, 771–773 (1976).
Spitzer G, Garson MO: Lymphoblastic leukemia with marked eosinophilia: A report of two cases.Blood 43, 377–384 (1973).
Chusid MJ, Dale DC, West BC, Wolff SM: The hypereosinophilic syndrome. Analysis of fourteen cases with review of the literature.Medicine 54, 1–27 (1975).
Fauci AS, moderator: The idiopathic hypereosinophilic syndrome. Clinical, pathophysiologic and therapeutic considerations.Ann Intern Med 97, 78–92 (1982).
Parillo JE, Fauci AS, Wolff SM: Therapy of the hypereosinophilic syndrome.Ann Intern Med 89, 167–172 (1978).
Parillo JE, Borer JS, Henry WL, Wolff SM, Fauci AS: The cardiovascular manifestations of the hypereosinophilic syndrome.Am J Med 67, 572–582 (1979).
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Merrick, Y., Rasmussen, L.P., Geisler, C. et al. Hypereosinophilia in a patient with acute lymphoblastic leukemia. Med. Oncol. & Tumor Pharmacother. 4, 97–100 (1987). https://doi.org/10.1007/BF02934946
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DOI: https://doi.org/10.1007/BF02934946