Abstract
Catalysis is the key technology for the development of green processes for the industrial production of active pharmaceutical ingredients. The design of green, efficient and cost competitive industrial process of idarubicin, erlotinib and ivermectin shows the central role of catalysis.
Riassunto
La catalisi: tecnologia fondamentale per it design di processi industriali a basso impatto ambientale nell'industria farmaceutica. La catalisi è la tecnologia fondamentale per lo sviluppo di processi industriali «green», efficienti e a basso costo per la produzione di idarubicina, erlotinib e ivermectina, dimostra il ruolo centrale dei processi catalitici.
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References
V. Murray (ed.),Major chemical disasters Medical aspects of management. International Congress and Symposium Series, n. 155, Royal Society of Medicine Services, London 1990.
P.T. Anastas—J.C. Warner,Green Chemistry: Theory and Practice. Oxford University Press, New York 1998.
J.L. Tucker, Org. Process Res. Dev., 10(2), 2006, 315–319.
S.J. Carey—D. Laffan—C. Thompson—M.T. Williams, Org. Biomol. Chem., 4, 2006, 2337–2347.
M.J. Braithwaite—C.L. Ketterman, Chem. Br., 29, 1993, 1042.
D.J. Cashman—G.E. Kellog, J. Med. Chem., 47, 2004, 1360–1374.
T. Komiyama—Y. Matsuzawa—T. Oki—T. Inui—Y. Takahashi —H. Naganawa—T. Takeuchi—H. Umezawa, J. Antibot., 30, 1977, 619–621.
W. Cabri—S. DeBernardinis—F. Francalanci—S. Penco, J. Chem. Soc. Perkin Trans., 1, 1990, 428.
F. Francalanci—W. Cabri—S. DeBernardinis—S. Penco—R. Santi, in:A.F. Noels, M. Graziani, A.J. Hubert (eds.),Metal Promoted Selectivity in Organic Synthesis. Catalysis by metal complexes, v. 12, Kuwler Academic, London 1991, 207–222.
W. Cabri, La Chimica e l'Industria, 75, 1993, 314.
W. Cabri—S. Di Fabio, in:From Bench to Market. The Evolution of Chemical Synthesis from Discovery to Industrial Production. Oxford University Press, Oxford 2000.
W. Cabri—V. Pizzamiglio—E. Mapelli, US6844455 (field 05.10.2001).
P.J. Stang—M.C. Hanack—L.R. Subramanian, Synthesis, 2, 1982, 85–124.
T.L. Petty, J. Clinical Oncology, 1, 2003, 3.
R.C. Schnur—L.D. Arnold, US5747498 (field 28 March 1996).
K. Sonogashira—Y. Tohda—N. Hagihara, Tetrahedron Lett., 1975, 16, 4467–4470.
R. Chinchilla—C. Najera, Chem. Rev., 107, 2007, 874–922.
W.B. Austin—N. Bilow—W.J. Kelleghan—K.S.J. Lau, J. Org. Chem., 48, 1981, 2280–2286.
R.F. Kovar—F.E. Arnold, US3975444 (filed 05.19.1975).
A. Burawoy—J.P. Critchley, Tetrahedron, 5, 1959, 340–351.
A. Onopchenko—E.T. Sabourin—C.M. Selwitz, US4139561 (filed 02.13.1979).
A. Onopchenko—E.T. Sabourin—C.M.Selwitz, US4215226 (filed 06.11.1978).
A. Onopchenko—E.T. Sabourin—C.M. Selwitz, J. Org. Chem., 44, 1979, 3671–3674.
A. Onopchenko—E.T. Sabourin—C.M. Selwitz, J. Org. Chem., 44, 1979, 1233–1236.
W. Cabri—E. Oldani, US5902902 (filed 02.12.1998 with priority IT1997 MI0002301 10.10.1997).
J.M. Gruber, US6225499 (filed 07.14. 1997).
J.C. Chabala—M.H. Fisher, US4199569 (filed 07.31.1978 priority US1977000838603 10.03. 1977).
T.G. Geary, Trends in Parasitology, 21, 2005, 530–532.
W.C. Campbell, Annu. Rev. Microbiol., 45, 1991, 445–474.
F.E. Roberts—V.J. Grenda, US4413118 (filed 03.02.1981).
C.J. Welch—J. Albaneze-Walker—W.R. Leonard—M. Biba—J. DaSilva—D. Henderson—B. Laing—D.J. Mathre—S. Spencer —S. Bu—T. Wang, Process Res. Dev., 9, 2005, 198–205.
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Cabri, W. Catalysis: A key technology for a green approach to pharmaceutical production. Rend. Fis. Acc. Lincei 18, 271–280 (2007). https://doi.org/10.1007/BF02934924
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DOI: https://doi.org/10.1007/BF02934924