Abstract
Objective: To investigate a new method of combined laparoscopy with Chinese herbal medicine (CHM) in treating endometrial ovarian cyst.
Methods
One hundred and fifty-two patients with endometrial ovarian cyst were randomly divided into 3 groups treated with three therapies: combined laparoscopy with CHM (combination group), CHM (TCM group) and danazol (WM group). To compare the clinical efficacy and sideeffects shown by the three groups and to elucidate the therapeutic mechanism by detecting the serum CA125 reproductive endocrine hormone, plasma prostaglandin F2a prostaglandin E2 etc.
Results
The shrinking rate, disappearance rate of the cysts and markedly effective rate in the combination group were obviously higher than those in the TCM group and WM group (P< 0.05,P<0.01). The pregnancy rate of combination group was also higher than that of the WM group (P<0.05). Few side-effects constituted the most prominent advantage for the combination group and TCM group. After treatment, the plasma prostaglandin F1a lowered remarkably, serum progesterone increased and CA125 reduced obviously (P<0.01,P<0.05).
Conclusion
The laparoscopy and CHM combination therapy is a new method in treating endometrial ovarian cyst which has significant efficacy, minimal adverse effect and maximal preservation of reproductive function.
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References
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Wu, YN., Hua, L., Jin, Y. et al. Clinical study on endometrial ovarian cyst treated by combined laparoscopy and chinese herbal medicine. CJIM 8, 11–15 (2002). https://doi.org/10.1007/BF02934610
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DOI: https://doi.org/10.1007/BF02934610