Abstract
One hundred and twenty-eight patients with active peptic ulcer were treated with Xilei powder for 4 weeks, their PGE2 levels in both serum and gastro-duodenal mucosa were significantly higher than those before treatment (P<0.01). The rate of negative conversion of Helicobacter pylori (HP) showed in 63.3% of cases. The distributed density of HP significantly reduced (P<0.01). These results indicated that Xilei powder could heal ulcer probably owing to the increasing of the PGE2 level in gastro-duodenal mucose, and inhibiting the growth and reproduction of HP so that to eliminate the HP, but did not owing to inhibit the gastric acid secretion and the release of gastrin.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Reference
Robert A, Schultz JR, Nezamis JE, et al. Gastric antisecretory and antiulcer properties of PGE2 15-mehtyl PGE2 and 16, 16-dimethyl PGE2. Gastroenterology 1976; 70(3): 359.
Vantrappen C. Effect of 15(R)-15-methy prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer. Gastroenterology 1982; 83(2): 357.
Graham DY. Campylobacter pylori and peptic ulcer. Gastroenterology 1989; 96(2): 615.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Zhang, AT., Qian, LX., Guan, JM. et al. Study on therapeutic mechanism of Xilei powder
for peptic ulcer) for peptic ulcer.
CJIM 2, 39–41 (1996). https://doi.org/10.1007/BF02934219
Issue Date:
DOI: https://doi.org/10.1007/BF02934219