Clinical study of the treatment based mainly on syndrome differentiation for the complications of bone marrow transplantation in 22 patients with leukemia

Abstract

Objective: To investigate the results of treatment of complications with traditional Chinese medicine (TCM) after bone marrow transplantation (BMT) in leukemic patients.Methods: Chinese herbal medicine was taken orally according to Syndrome Differentiation.Results: Ten patients with long-term fever (9 patients with unknown causes, 1 patient with lung infection) were cured, who were irresponsive to the combination of multi-antibiotics. Out of 3 patients with severe jaundice, it was cured in 1 patient with hepatic venoocclusive disease (VOD), and improved after treatment of TCM and deteriorated secondary to severe infection in the other 2 patients with graft versus-host-disease. Out of 9 patients with gastrointestinal side effects induced by high-dose radiotherapy or chemotherapy, it was cured in 6 patients, improved in 2 patients and no response in 1 patient.Conclusion: TCM was showed to be effective in treating the complications post-BMT in patients with leukemia, and could accelerate the recovery of patients.