Abstract
For the purpose of mass producingMonascus red pigments optimum medium composition and environmental conditions were investigated in submerged flask cultures. The optimum carbon and nitrogen sources were determined to be 30 g/L of glucose and 1.5 g/L of monosodium glutamate (MSG). Of the three metals examined, Fe2+ showed the stronges stimulatory effect on pigment production and some stimulatory effect was also found in Mn2+. Optimum pH and agitation speed were determined to be 6.5 and 700 rpm, respectively. Under the optimum culture conditions batch fermentation showed that the maximum biomass yield and specific productivity of red pigments were 0.20 g DCW/g glucose and, 32.5 OD500 g DCW−1 h−1, respectively.
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Lee, BK., Park, NH., Piao, H.Y. et al. Production of red pigments byMonascus purpureus in submerged culture. Biotechnol. Bioprocess Eng. 6, 341–346 (2001). https://doi.org/10.1007/BF02933003
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DOI: https://doi.org/10.1007/BF02933003