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Left-to-right shunts

Quantification, mathematical methods and their statistical comparison

  • Nuclear Medicine Section
  • Original Contributions
  • Published:
Ricerca in clinica e in laboratorio

Summary

This work describes a non-traumatic technique for quantitative determination of left-to-right shunts. Various mathematical methods to evaluate the radioisotope concentration lung curve are considered. Data were collected with a γ camera system connected to a computer. The first results were obtained from 18 patients at theOspedali Riuniti in Parma, Italy. All the mathematical processes are described. The three methods used were based on: 1. the count ratio (C2/C1) between two pulmonary activity concentrations, 2. the γ function fitting, 3. decreasing exponential A comparison of the three methods shows that the γ function method is the most reliable. In this kind of investigation the patient's radiation dose is low enough for it to be repeated so that the course of the disease can be followed.

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Authors and Affiliations

  1. Servizio di Fisica Sanitaria degli Ospedali Riuniti di Parma, Ospedali Riuniti di Parma, Via A. Gramsci 14, 43100, Parma, Italia

    Pier Paolo Ferretti, Anna Benini & Adriano Borrini

  2. Istituto di Radiologia Medica e Medicina Nucleare, Parma, Italia

    Giorgio Ugolotti

Authors
  1. Pier Paolo Ferretti
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  2. Anna Benini
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  3. Adriano Borrini
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  4. Giorgio Ugolotti
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Ferretti, P.P., Benini, A., Borrini, A. et al. Left-to-right shunts. La Ricerca Clin. Lab. 9, 295–305 (1979). https://doi.org/10.1007/BF02932181

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  • DOI: https://doi.org/10.1007/BF02932181

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